Advertisement

Topics

Hydrogen peroxide mediates triclosan-induced inhibition of root growth in wheat seedlings.

08:00 EDT 4th September 2018 | BioPortfolio

Summary of "Hydrogen peroxide mediates triclosan-induced inhibition of root growth in wheat seedlings."

Triclosan, an extensively used antimicrobial agent, enters agroecosystems when sewage sludge and reclaimed water are applied to agricultural fields, and may trigger a series of plant physiological and biochemical responses. However, few studies have investigated the mechanism by which plant development is affected by triclosan. Here, microscopic, pharmacological and biochemical analyses, and histochemical dye staining were used to explore the effects of triclosan on root growth in wheat plants. Exposure to triclosan inhibited root elongation, and significantly triggered hydrogen peroxide (HO) production and lipid peroxidation in wheat roots. The inhibition of root growth by triclosan was reversed by dimethylthiourea, a HO scavenger, indicating that alterations of endogenous HO concentrations in root cells were likely linked to triclosan-induced root growth inhibition. The addition of butylated hydroxyanisole, a lipophilic antioxidant, during triclosan treatment completely prevented the increase of lipid peroxidation, but did not alleviate triclosan-induced reduction of root growth. In triclosan-treated wheat roots, the level of indole-3-acetic acid decreased by 68.3%, while the contents of two indole-3-acetic acid oxidative metabolites, indole-3-aldehyde and indole-3-carboxylic acid, increased by 71.3% and 314.4%, respectively. Moreover, the oxidation of auxin induced by triclosan in wheat roots was prevented by dimethylthiourea. These results together suggested that the triclosan-enhanced production of HO induced auxin oxidation, thus leading to the suppression of root growth. Findings of this study improve our mechanistic understanding on how antimicrobial agents such as triclosan affect plant root growth.

Affiliation

Journal Details

This article was published in the following journal.

Name: Environmental pollution (Barking, Essex : 1987)
ISSN: 1873-6424
Pages: 472-479

Links

DeepDyve research library

PubMed Articles [22827 Associated PubMed Articles listed on BioPortfolio]

Exogenous hydrogen peroxide inhibits primary root gravitropism by regulating auxin distribution during Arabidopsis seed germination.

Hydrogen peroxide (HO) is the key factor in many physiological and metabolic processes in plants. During seed germination, exogenous HO application influences gravitropism and induces curvature of the...

Omeprazole enhances mechanical stress-induced root growth reduction in Arabidopsis thaliana.

Mechanical sensing is one of the most fundamental processes for sessile plants to survive and grow. The response is known to involve calcium elevation in the cell. The Arabidopsis seedlings grown hori...

microRNA-29a inhibition induces Gab1 upregulation to protect OB-6 human osteoblasts from hydrogen peroxide.

The present study determines the role of the Gab1 in hydrogen peroxide (HO)-induced death of human osteoblasts. We show that Gab1 is required for HO-induced Akt activation to promote osteoblast surviv...

Spermidine-mediated hydrogen peroxide signaling enhances the antioxidant capacity of salt-stressed cucumber roots.

Hydrogen peroxide (HO) is a key signaling molecule that mediates a variety of physiological processes and defense responses against abiotic stress in higher plants. In this study, our aims are to clar...

Ethylene-induced microtubule reorientation is essential for fast inhibition of root elongation in Arabidopsis.

Microtubule reorientation is a long-standing observation that has been implicated in regulating the inhibitory effect of ethylene on axial elongation of plant cells. However, the signaling mechanism u...

Clinical Trials [7142 Associated Clinical Trials listed on BioPortfolio]

Adjunctive Hydrogen Peroxide for Periodontal Therapy

There have been many adjunctive treatments for the additional clinical benefits to scaling and root planing (SRP) in the treatment of chronic periodontitis. Topical hydrogen peroxide (HP) ...

Combination of Dental Bleaching Techniques, Randomized Clinical Trial

To determine the effectiveness of combining different concentrations of hydrogen peroxide and carbamide used during tooth bleaching.

Bleaching Tooth of Low Concentration Domestic and Office

To evaluate the efficacy, safety and impact on quality of life related to oral health of home and office tooth whitening techniques in young individuals.

Wound Healing of Incisional Wounds for Bilateral Hernia Repair

The purpose of this research study is to test the safety of an oxygen producing gel (produced by combining baking soda and hydrogen peroxide) and see what effects (good and bad) it has on ...

EXhaled Hydrogen Peroxide As a Marker of Lung diseasE (EXHALE) Pilot Study.

This Pilot study evaluates the use of a new device called Inflammacheck and whether it can consistently measure hydrogen peroxide levels in exhaled breath condensate. It will also assess w...

Medical and Biotech [MESH] Definitions

Chemicals used mainly to disinfect root canals after pulpectomy and before obturation. The major ones are camphorated monochlorophenol, EDTA, formocresol, hydrogen peroxide, metacresylacetate, and sodium hypochlorite. Root canal irrigants include also rinsing solutions of distilled water, sodium chloride, etc.

An oxidoreductase that catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide. EC 1.15.1.1.

A hemeprotein which catalyzes the oxidation of ferrocytochrome c to ferricytochrome c in the presence of hydrogen peroxide. EC 1.11.1.5.

Peroxidase catalyzed oxidation of lipids using hydrogen peroxide as an electron acceptor.

An enzyme of the oxidoreductase class that catalyzes the conversion of beta-D-glucose and oxygen to D-glucono-1,5-lactone and peroxide. It is a flavoprotein, highly specific for beta-D-glucose. The enzyme is produced by Penicillium notatum and other fungi and has antibacterial activity in the presence of glucose and oxygen. It is used to estimate glucose concentration in blood or urine samples through the formation of colored dyes by the hydrogen peroxide produced in the reaction. (From Enzyme Nomenclature, 1992) EC 1.1.3.4.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article