Evaluating the Use of Silicone Wristbands to Measure Personal Exposure to Brominated Flame Retardants.

08:00 EDT 14th September 2018 | BioPortfolio

Summary of "Evaluating the Use of Silicone Wristbands to Measure Personal Exposure to Brominated Flame Retardants."

Biomarkers remain the gold standard for assessing chemical exposure. However, silicone wristbands may provide some added benefits for characterizing personal exposures compared to single biomarker measurements such as decreased costs, non-invasive sampling, and increased ease of analysis. Previously, we demonstrated that wristbands could be used effectively to characterize exposure to organophosphate flame retardants (PFRs), which have short half-lives in the body. However, it is unclear whether these results would extend to chemicals like polybrominated diphenyl ethers (PBDEs), which biomagnify and have longer half-lives than PFRs in the body. This study sought to determine if accumulation of PBDEs on wristbands was correlated to serum biomarkers. Adult participants (n=30) provided serum samples and wore wristbands for 7 days. PBDEs and 6 novel brominated flame retardants (BFRs) were measured on wristbands, and serum samples were analyzed for PBDE biomarkers. Like most PBDE congeners, 5 of 6 novel BFRs were detected on wristbands frequently (≥90% of bands). In particular, decabromodiphenyl ethane (DBDPE) was detected in all wristbands in this study and was significantly correlated with BDE-209, suggesting a similar source and exposure pathway. Wristband levels of BDE-47, -99, -100, and -153 were significantly and positively associated with respective serum biomarkers (rs=0.39-0.57, p<0.05). This study demonstrates that silicone wristbands can be used to measure personal PBDE exposures.


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This article was published in the following journal.

Name: Environmental science & technology
ISSN: 1520-5851


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