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The role of substance use, smoking, and inflammation in risk for suicidal behavior.

08:00 EDT 7th September 2018 | BioPortfolio

Summary of "The role of substance use, smoking, and inflammation in risk for suicidal behavior."

Alcohol and substance use disorders are important predictors for suicidal behavior. However, the role of individual substances as proximal risk factors for suicidal behavior and the mechanisms through which substance use affect risk are not entirely clear. We examine whether the frequency of substance use and whether biological markers in the HPA axis and inflammatory pathways are associated with clinical risk factors of suicidal behavior of aggression, impulsivity, hopelessness, and poor sleep.

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This article was published in the following journal.

Name: Journal of affective disorders
ISSN: 1573-2517
Pages: 33-41

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Medical and Biotech [MESH] Definitions

A risk factor for suicide attempts and completions, it is the most common of all suicidal behavior, but only a minority of ideators engage in overt self-harm.

Motivational state produced by inconsistencies between simultaneously held cognitions or between a cognition and behavior; e.g., smoking enjoyment and believing smoking is harmful are dissonant.

Reduction of high-risk choices and adoption of low-risk quantity and frequency alternatives.

A decrease in the incidence and frequency of SMOKING. Smoking reduction differs from SMOKING CESSATION in that the smoker continues to smoke albeit at a lesser frequency without quitting.

Motor behavior that is repetitive, often seemingly driven, and nonfunctional. This behavior markedly interferes with normal activities or results in severe bodily self-injury. The behavior is not due to the direct physiological effects of a substance or a general medical condition. (DSM-IV, 1994)

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