Granular cell tumor in a premenstrual female breast.
Summary of "Granular cell tumor in a premenstrual female breast."
Granular cell tumor is an exceedingly rare pediatric breast mass, derived from Schwann cells which are most commonly observed in the oral cavity, skin, and subcutaneous tissue. When they occur in the breast, they can mimic intrinsic breast masses. Most cases are benign, but malignant cases have been reported. We present a case of a premenstrual, African-American 9 year old female with a painful right breast mass originally felt to be an epidermal inclusion cyst. An ultrasound was performed 17 months after original presentation which demonstrated a 1 cm well-circumscribed solid ovoid mass. Despite the relatively small size and benign imaging appearance of the mass, surgical resection was performed for symptom relief given the associated pain. This is the first known case of granular cell tumor of the breast in a premenstrual female.
Affiliation
Journal Details
This article was published in the following journal.
Name: Clinical imaging
ISSN: 1873-4499
Pages: 334-336
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/30241035
- DOI: http://dx.doi.org/10.1016/j.clinimag.2018.09.003
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Medical and Biotech [MESH] Definitions
Premenstrual Dysphoric Disorder
A condition in which a woman suffers from severe depression, irritability, and tension before MENSTRUATION. Premenstrual dysphoric disorder (PMDD) may involve a wide range of physical or emotional symptoms, which are more severe and debilitating than those seen with premenstrual syndrome (PMS), and which include at least one mood-related symptom. Symptoms usually stop when, or shortly after, menstruation begins.
Granular Cell Tumor
Unusual tumor affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead to proliferation of the squamous cells and mimic squamous cell carcinoma.
Mesonephroma
A rare tumor of the female genital tract, most often the ovary, formerly considered to be derived from mesonephric rests. Two varieties are recognized: (1) clear cell carcinoma, so called because of its histologic resemblance to renal cell carcinoma, and now considered to be of muellerian duct derivation and (2) an embryonal tumor (called also ENDODERMAL SINUS TUMOR and yolk sac tumor), occurring chiefly in children. The latter variety may also arise in the testis. (Dorland, 27th ed)
Ultrasonography, Mammary
Use of ultrasound for imaging the breast. The most frequent application is the diagnosis of neoplasms of the female breast.
Genital Neoplasms, Female
Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE).
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