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Selenium-lentinan inhibits tumor progression by regulating epithelial-mesenchymal transition.

08:00 EDT 18th September 2018 | BioPortfolio

Summary of "Selenium-lentinan inhibits tumor progression by regulating epithelial-mesenchymal transition."

Selenium supplementation can be used to treat tumors. However, inorganic selenium is highly toxic, and natural organic selenium is extremely rare. Polysaccharides can improve drug bioavailability and targeting. Lentinan is a polysaccharide that has been approved as an anti-cancer drug in Japan and China.

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This article was published in the following journal.

Name: Toxicology and applied pharmacology
ISSN: 1096-0333
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Phenotypic changes of EPITHELIAL CELLS to MESENCHYME type, which increase cell mobility critical in many developmental processes such as NEURAL TUBE development. NEOPLASM METASTASIS and DISEASE PROGRESSION may also induce this transition.

A selenium compound used as a source of SELENIUM, especially for patients that develop selenium deficiency following prolonged PARENTERAL NUTRITION.

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