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Analysis of the dissipation kinetics of thiophanate-methyl and its metabolite carbendazim in apple leaves using a modified QuEChERS-UPLC-MS/MS method.

08:00 EDT 24th September 2018 | BioPortfolio

Summary of "Analysis of the dissipation kinetics of thiophanate-methyl and its metabolite carbendazim in apple leaves using a modified QuEChERS-UPLC-MS/MS method."

As one of the main fungicides for the apple leaf disease control, thiophanate-methyl (TM) mainly exerts the fungicidal activity in the form of its metabolite carbendazim (MBC), whose dissipation kinetics is very distinct from its parent but was paid little attention. The aim of this work was to investigate the dissipation kinetics of TM and its active metabolite MBC in apple leaves using a modified QuEChERS-UPLC-MS/MS method. Results showed TM and MBC could be quickly extracted by this modified QuEChERS procedure with the recoveries of 81.7%-96.5%. The method linearity was in the range of 0.01-50.0 mg kg with the quantification limit of 0.01 mg kg . Then this method was applied to the analysis of fungicide dissipation kinetics in apple leaves. Results showed the dissipation kinetics of TM for the test in three months can be described by the first order kinetics model with the DT (dissipation half-life) range of 5.23-6.03 days and the kinetics for MBC can be described by the first order absorption-dissipation model with the T (time needed to reach most concentration) range of 4.78-7.09 days. These models can scientifically describe the behavior of TM and MBC in apple leaves, which provide necessary data for the scientific use.

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Journal Details

This article was published in the following journal.

Name: Biomedical chromatography : BMC
ISSN: 1099-0801
Pages: e4394

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