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Whole genome sequencing reveals genetic signature of bedaquiline resistance in a clinical isolate of Mycobacterium tuberculosis.

08:00 EDT 21st September 2018 | BioPortfolio

Summary of "Whole genome sequencing reveals genetic signature of bedaquiline resistance in a clinical isolate of Mycobacterium tuberculosis."

Emergence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) strains have opened new challenges for tuberculosis control in India. This study examined molecular markers of resistance to bedaquiline, a new antituberculous drug with a potential to dramatically improve MDR-TB treatment outcomes and reduce mortality.

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This article was published in the following journal.

Name: Journal of global antimicrobial resistance
ISSN: 2213-7173
Pages:

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Medical and Biotech [MESH] Definitions

Techniques to determine the entire sequence of the GENOME of an organism or individual.

Change brought about to an organisms genetic composition by unidirectional transfer (TRANSFECTION; TRANSDUCTION, GENETIC; CONJUGATION, GENETIC, etc.) and incorporation of foreign DNA into prokaryotic or eukaryotic cells by recombination of part or all of that DNA into the cell's genome.

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