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Using clinical and genetic data to predict pulmonary hypertension in bronchopulmonary dysplasia.

08:00 EDT 29th September 2018 | BioPortfolio

Summary of "Using clinical and genetic data to predict pulmonary hypertension in bronchopulmonary dysplasia."

Pulmonary hypertension significantly increases morbidity and mortality in infants with bronchopulmonary dysplasia. The frequency of single nucleotide polymorphisms in arginase-1 (ARG1 rs2781666) and dimethylarginine dimethylaminohydrolase-1 (DDAH1 rs480414) genes have been found to differ in a cohort of bronchopulmonary dysplasia patients with pulmonary hypertension (cases) and without pulmonary hypertension (controls). Therefore, we tested the hypothesis that combining these genotypes with phenotypic data would better predict pulmonary hypertension in bronchopulmonary dysplasia patients.

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This article was published in the following journal.

Name: Acta paediatrica (Oslo, Norway : 1992)
ISSN: 1651-2227
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