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Mixed particle beam for simultaneous treatment and on-line range verification in carbon ion therapy: proof of concept study.

08:00 EDT 30th September 2018 | BioPortfolio

Summary of "Mixed particle beam for simultaneous treatment and on-line range verification in carbon ion therapy: proof of concept study."

Radiation therapy with ion beams provides a better conformation and effectiveness of the dose delivered to the tumor with respect to photon beams. This implies that a small uncertainty or variation in the crossed tissue shape and density may lead to a more important underdosage of the tumor and/or an overdosage of the surrounding healthy tissue. Although the on-line control of beam fluence and transverse position is well managed by an appropriate beam delivery system, the on-line measurement of the longitudinal position of the Bragg peak inside the patient is still an open issue. In this paper we propose a proof of concept study of a technique that would allow the online verification of the patient thickness along the beam direction, which could permit detecting a subset of possible range error causes, such as morphological variations.

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Name: Medical physics
ISSN: 2473-4209
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Medical and Biotech [MESH] Definitions

A technique used to separate particles according to their densities in a continuous density gradient. The sample is usually mixed with a solution of known gradient materials and subjected to centrifugation. Each particle sediments to the position at which the gradient density is equal to its own. The range of the density gradient is usually greater than that of the sample particles. It is used in purifying biological materials such as proteins, nucleic acids, organelles, and cell types.

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The use of a heavy ion particle beam for radiotherapy, such as the HEAVY IONS of CARBON.

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