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Evolution of living systems is a succession of historical changes in their equilibrium states. In the individual life cycle, every such state is realized as an equilibrium of developmental system, i.e. as its adult organizational norm. A trigger for a switching the system to a search for a new equilibrium is the loss under critical conditions of effective regulation of normal development towards uniform final state. This is manifested by replacement of the adult norm by its individual deviations. Thus, the organizational change begins with its adult state, which is the first to undergo the disturbance under new conditions. Accordingly, with the transition of the organization to a new equilibrium, the remodeling of the developmental system extends in generations from the adult stage to earlier ones. These premises contrast with the accepted belief that evolutionary events begin with individual changes in the germ cell. The only substantiated alternative to the last approach is objectively presented by the concepts of Schmalhausen and Waddington, in which the change in systemic organization starts with stabilization of selected phenotypic variations generated by violation of the current adult norm. The evolutionary spreading of organizational changes towards the early developmental stages constitutes in this case a natural consequence of the stabilization process. This course of events is actually reflected in different ways in the many empirical generalizations that have grown in the scope of more traditional views. It may be predicted that this pattern will come to provide a basis for a revised understanding of the evolutionary process.
This article was published in the following journal.
Name: Bio Systems
Extant literature suggested that positive organizational climate leads to higher levels of organizational commitment, which is an important concept in terms of employee attitudes, likewise, the concep...
Organizational health literacy is the degree to which an organization considers and promotes the health literacy of patients. Addressing health literacy at an organizational level has the potential to...
There is at present no standard methodology to analyse the organizational impacts (OIs) of medical devices (MDs), and the field is still in its infancy. The aim of the present study was to assess, at ...
'In this method note, we question if the primary search strategy in a systematic review should be accompanied by a search narrative. A search narrative could offer a conceptual and contextual report o...
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The purpose of this trial is to investigate the effect of organizational skills training, a parent and child training approach on organizational skills, inattentive symptoms and functional...
This study aims to describe in depth the CNS, CNS HIV reservoir and CNS viral rebound in consenting SEARCH 019 subjects prior to, during and after the SEARCH 019 study intervention (VHM + ...
This study will evaluate the effectiveness of organizational skills training in improving organizational, time management, and planning difficulties in children with attention deficit hype...
There are large differences in knowledge between patients and healthcare providers (i.e. physicians, physician assistants and nurse practitioners), and there is a strong interest on the pa...
To evaluate the impact of organizational-level health promotion activities and worksite characteristics on employee dietary and smoking behaviors.
The interdisciplinary science that studies evolutionary biology, including the origin and evolution of the major elements required for life, their processing in the interstellar medium and in protostellar systems. This field also includes the study of chemical evolution and the subsequent interactions between evolving biota and planetary evolution as well as the field of biology that deals with the study of extraterrestrial life.
Evolution at the molecular level of DNA sequences and proteins. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
The techniques used to produce molecules exhibiting properties that conform to the demands of the experimenter. These techniques combine methods of generating structural changes with methods of selection. They are also used to examine proposed mechanisms of evolution under in vitro selection conditions.
A love or pursuit of wisdom. A search for the underlying causes and principles of reality. (Webster, 3d ed)
The systematic search and discovery of natural substances which may have potential commercial applications.