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Transforaminal interbody debridement and fusion to manage post-discectomy discitis in lumbar spine.

08:00 EDT 8th October 2018 | BioPortfolio

Summary of "Transforaminal interbody debridement and fusion to manage post-discectomy discitis in lumbar spine."

Traditionally, non-operative management with long-term antibiotics and bed rest has been recommended as the first-line treatment for most post-operative discitis patients. However, a recent trend in treatment under a limited range of indications has been to perform surgical debridement followed by the long-term administration of antibiotics. This descriptive study investigated whether transforaminal lumbar interbdoy debridement and fusion (TLIDF) combined with intravenous antibiotics is appropriate to manage post-discectomy discitis.

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This article was published in the following journal.

Name: World neurosurgery
ISSN: 1878-8769
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Medical and Biotech [MESH] Definitions

Inflammation of an intervertebral disk or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.

The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.

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The GENETIC RECOMBINATION of the parts of two or more GENES, including an ONCOGENE as at least one of the fusion partners. Such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS.

Use of a metal casting, usually with a post in the pulp or root canal, designed to support and retain an artificial crown.

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