Genetic diversity of porcine circovirus type 2 in China between 1999-2017.

08:00 EDT 11th October 2018 | BioPortfolio

Summary of "Genetic diversity of porcine circovirus type 2 in China between 1999-2017."

Porcine circovirus type 2 (PCV-2), is linked to PCV-2 associated disease, which has caused considerable economic loss in the swine industry. Here, we report the genetic diversity of PCV-2 in China. A total of 74 Chinese PCV-2 strains sequenced between 1999 and 2017 were studied. Based on the ORF2 and complete genomes, we found that apart from the PCV-2a, PCV-2b, and PCV-2d genotypes, two unstable recombination genotypes also exist, referred to as IM1 and IM2 genotypes. We found that the patterns of PCV-2 genetic shift in China are similar to the patterns at the global level. Additionally, for the PCV-2 ORF2 gene of Chinese isolates, we found a similar time to the most recent common ancestor and evolutionary rate to the global values. This indicates that PCV2 genetic diversity in China is driven by genetic drift/recombination of local strains and by the sporadic introduction of foreign genotypes from other countries. Overall, our study illustrates the genetic diversity and evolution dynamics of PCV-2 in China. This article is protected by copyright. All rights reserved.


Journal Details

This article was published in the following journal.

Name: Transboundary and emerging diseases
ISSN: 1865-1682


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