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A variable course of Cushing's disease in a 7 year old: diagnostic dilemma.

08:00 EDT 12th October 2018 | BioPortfolio

Summary of "A variable course of Cushing's disease in a 7 year old: diagnostic dilemma."

Cushing's syndrome (CS) or hypercortisolism results from disruption of the hypothalamus-pituitary-adrenal (HPA) axis with the resultant increase in the circulating serum and urinary cortisol levels and lack of cortisol circadian rhythm. The resultant effects cause the physical manifestation of hypercortisolism. The appearance of Cushing's disease in children is insidious, the most common features being growth failure, obesity, early puberty and facial appearance. We report a case of a 7-year-old male with a very unusual course of the disease, which could have led to diagnostic delays.

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This article was published in the following journal.

Name: Journal of pediatric endocrinology & metabolism : JPEM
ISSN: 2191-0251
Pages:

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