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The identification of materials with beneficial properties for wound healing is a major research goal. In this study, gelatin was used as a reducing agent and stabilizer to restore silver nanoparticles (AgNPs) in situ, which were mixed with chitosan (CS), crosslinked with tannic acid, and then freeze-dried to obtain a new composite Gelatin/CS/Ag. Gelatin/CS/Ag has a dense pore structure with a pore size of about 100-250 μm. The pores were interconnected. The existence of AgNPs was proven by UV visible spectrophotometry, XRD, and electron microscopy. Gelatin/CS/Ag exhibited good mechanical properties, water absorption, and moisture retention. The material was evaluated in antibacterial experiments, and a good inhibitory effect of Gelatin/CS/Ag was observed. Gelatin/CS/Ag co-cultured with L929 cells did not show cytotoxicity. Finally, Gelatin/CS/Ag promoted wound healing and showed good biocompatibility. In summary, Gelatin/CS/Ag has promising antibacterial and wound healing properties.
This article was published in the following journal.
Name: International journal of biological macromolecules
In the present study, we have successfully prepared tasar fibroin nanofibrous mats using 1‑butyl‑3‑methylimidazolium acetate for skin tissue engineering. The prepared tasar nanofibrous mat was f...
In the present study, poly(vinyl alcohol) (PVA) - Acacia lignin (PL) nanofiber mats loaded with silver nanoparticles were prepared and characterized. In-situ synthesis of silver nanoparticles was acco...
Although silver nanoparticles are the most widespread product of nanotechnology, the mechanisms underlying AgNP microbial toxicity remain the subject of intense debate. In this study, Bacillus subtili...
The authors describe a simplified chemical precipitation method and silver mirror reaction to synthesize a nanocomposite consiting of silver nanoparticles on a thin and porous nickel oxide film. Place...
Green synthesis of metallic nanoparticles has attracted a great deal of attention from scientific community due to its biocompatibility and environment friendly nature. In the present study, silver na...
Silver nanoparticles are one of most nanoparticles use nowadays in the research area because it has specific physical and chemical properties, in medical fields silver nanoparticles can in...
The purpose of this study is to determine whether oral topic silver nanoparticles are effective to reduce potential pathogen microbial loads in mechanical ventilation patients.
Chronic rhinosinusitis is a highly prevalent disease resulting in high economic burden. Effective therapeutic options are needed. Rhinosinusitis-related biofilms are a likely contributor t...
Bloodstream infections are common in Intensive Care Units (ICUs). The need of a central venous line increases the risk of bacteremia and central venous catheter (CVC) related infections. T...
Silver nitrate treatment of Bartholin's cyst or abscess will be compared to marsupialization treatment. It is expected that silver nitrate treatment is effective, simple, inexpensive and ...
The use of silver, usually silver nitrate, as a reagent for producing contrast or coloration in tissue specimens.
Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
Nanoparticles produced from metals whose uses include biosensors, optics, and catalysts. In biomedical applications the particles frequently involve the noble metals, especially gold and silver.
Inorganic compounds that contain silver as an integral part of the molecule.
A silver salt with powerful germicidal activity. It has been used topically to prevent OPHTHALMIA NEONATORUM.
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...
Complementary and Alternative Medicine
Alternative medicine are whole medical systems that did not fit with conventional medicine as they have completely different philosophies and ideas on the causes of disease, methods of diagnosis and approaches to treatment. Although often overlapping, co...