Placental inflammation, lifestyle, maternal and early child sensitization to allergens - the ALADDIN birth cohort.

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Summary of "Placental inflammation, lifestyle, maternal and early child sensitization to allergens - the ALADDIN birth cohort."

To investigate; i) if maternal sensitization to allergens, and lifestyle can influence the risk of acute as well as chronic inflammation of the placenta, in the forms of chorioamnionitis and villitis, respectively, and ii) if these placental inflammations are associated with the outcome of sensitization for the child during preschool age.


Journal Details

This article was published in the following journal.

Name: Acta paediatrica (Oslo, Norway : 1992)
ISSN: 1651-2227


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Medical and Biotech [MESH] Definitions

Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission.

A lectin that binds CHITIN, but lacks chitinase activity. It may be involved in tissue remodeling and cellular responses to the environment, including the response of type 2 HELPER T-CELLS to INFLAMMATION and sensitization to ALLERGENS. Mutations in the CHI3L1 gene are associated with ASTHMA.

A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES).

An inflammation of the NASAL MUCOSA triggered by ALLERGENS.

Transmission of genetic characters, qualities, and traits, solely from maternal extra-nuclear elements such as MITOCHONDRIAL DNA or MATERNAL MESSENGER RNA.

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Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...

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