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Elevated IgE M1 prime transcripts in nasal tissues in patients with nasal polyps and asthma.

08:00 EDT 22nd October 2018 | BioPortfolio

Summary of "Elevated IgE M1 prime transcripts in nasal tissues in patients with nasal polyps and asthma."

A novel PCR assay detected IgE M1 prime transcripts in nasal polyps of patients with CRSwNP and asthma, confirming that IgE switching occurred and membrane IgE-expressing B cells were resident at mucosal sites.

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Journal Details

This article was published in the following journal.

Name: The Journal of allergy and clinical immunology
ISSN: 1097-6825
Pages:

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Medical and Biotech [MESH] Definitions

Fluid obtained by irrigation or washout of the nasal cavity and NASAL MUCOSA. The resulting fluid is used in cytologic and immunologic assays of the nasal mucosa such as with the NASAL PROVOCATION TEST in the diagnosis of nasal hypersensitivity.

The proximal portion of the respiratory passages on either side of the NASAL SEPTUM. Nasal cavities, extending from the nares to the NASOPHARYNX, are lined with ciliated NASAL MUCOSA.

Application of allergens to the nasal mucosa. Interpretation includes observation of nasal symptoms, rhinoscopy, and rhinomanometry. Nasal provocation tests are used in the diagnosis of nasal hypersensitivity, including RHINITIS, ALLERGIC, SEASONAL.

Diagnostic measurement of the nose and its cavity through acoustic reflections. Used to measure nasal anatomical landmarks, nasal septal deviation, and nasal airway changes in response to allergen provocation tests (NASAL PROVOCATION TESTS).

The partition separating the two NASAL CAVITIES in the midplane. It is formed by the SEPTAL NASAL CARTILAGE, parts of skull bones (ETHMOID BONE; VOMER), and membranous parts.

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