Advertisement

Topics

Evaluating cellularity and structural connectivity on whole brain slides using a custom-made digital pathology pipeline.

08:00 EDT 23rd October 2018 | BioPortfolio

Summary of "Evaluating cellularity and structural connectivity on whole brain slides using a custom-made digital pathology pipeline."

In brain research, the histopathological examination of coronar whole-brain slides provides important insights into spatial disease characteristics. Regarding brain tumor research, this enables visualization of tumor heterogeneity, infiltration patterns and the relationship with the surrounding brain parenchyma. The precise correlation between radiological imaging and post-mortem brains is of special interest.

Affiliation

Journal Details

This article was published in the following journal.

Name: Journal of neuroscience methods
ISSN: 1872-678X
Pages:

Links

DeepDyve research library

PubMed Articles [13707 Associated PubMed Articles listed on BioPortfolio]

Quantification of structural brain connectivity via a conductance model.

Connectomics has proved promising in quantifying and understanding the effects of development, aging and an array of diseases on the brain. In this work, we propose a new structural connectivity measu...

Internet gaming disorder: deficits in functional and structural connectivity in the ventral tegmental area-Accumbens pathway.

Dopamine projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) and from the substantia nigra (SN) to the dorsal striatum are involved in addiction. However, relatively littl...

Reproducibility and intercorrelation of graph theoretical measures in structural brain connectivity networks.

Diffusion-weighted magnetic resonance imaging can be used to non-invasively probe the brain microstructure. In addition, recent advances have enabled the identification of complex fiber configurations...

Polygenic risk score for schizophrenia and structural brain connectivity in older age: A longitudinal connectome and tractography study.

Higher polygenic risk score for schizophrenia (szPGRS) has been associated with lower cognitive function and might be a predictor of decline in brain structure in apparently healthy populations. Age-r...

Structure-function multi-scale connectomics reveals a major role of the fronto-striato-thalamic circuit in brain aging.

Physiological aging affects brain structure and function impacting morphology, connectivity, and performance. However, whether some brain connectivity metrics might reflect the age of an individual is...

Clinical Trials [7551 Associated Clinical Trials listed on BioPortfolio]

Brain Excitability and Connectivity in Sensory-motor Pathways in ALS

The main objective is to determine the origin of somatosensory alteration in patients with ALS and to evaluate its impact on brain activity by coupling different imaging modalities and ind...

Structural and Functional Connectivity in Autism Spectrum Disorders

Autism spectrum disorder (ASD) has been given a high priority for genetic and neurobiological study. There is no such information in Asian population and no study has conducted using Diffu...

Anatomical and Structural Connectivity in Two Psychotic Phenotypes : Periodic Catatonia and Cataphasia

The different subtypes of Schizophrenia might have a disordered connectivity as their final common pathways. The investigators will use multimodal structural MRI to assess anatomical conn...

Impact of Epileptic Discharge on the Structural Connectivity of the Developing Brain

Focal epilepsy is associated with widespread alterations in structural brain connectivity, often present at the disease onset and related to learning disabilities. Whether ongoing seizure ...

Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder

Lithium is highly effective in the treatment of bipolar disorder. This study aims to investigate, for the first time, the impact of lithium monotherapy on the structural and functional con...

Medical and Biotech [MESH] Definitions

An organized procedure carried out by a select committee of professionals in evaluating the performance of other professionals in meeting the standards of their specialty. Review by peers is used by editors in the evaluation of articles and other papers submitted for publication. Peer review is used also in the evaluation of grant applications. It is applied also in evaluating the quality of health care provided to patients.

A cellular phone with advanced computing and connectivity capability built on an operating system.

The simultaneous analysis of multiple samples of TISSUES or CELLS from BIOPSY or in vitro culture that have been arranged in an array format on slides or microchips.

Individuals connecting by family, work or other interests. It also includes connectivity facilitated by computer-based communications.

Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article