Serum Concentrations of Lidocaine During Bariatric Surgery.
Summary of "Serum Concentrations of Lidocaine During Bariatric Surgery."
Lidocaine has been shown to be clinically beneficial during bariatric surgery. However, information about lidocaine serum concentrations in this setting is scarce. This prospective clinical trial included 42 obese patients undergoing laparoscopic bariatric surgery. They received lidocaine based on adjusted body weight. Administration began with a 1.5 mg·kg bolus of intravenous lidocaine followed by a continuous infusion of 2 mg·kg·hour. After skin closure, administration was decreased to 1 mg·kg·hour until discharge from the recovery room. No serum concentrations of lidocaine were outside the usual accepted range (1.5-5 µg·mL).
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Journal Details
This article was published in the following journal.
Name: Anesthesia and analgesia
ISSN: 1526-7598
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/30399021
- DOI: http://dx.doi.org/10.1213/ANE.0000000000003905
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Medical and Biotech [MESH] Definitions
Bariatric Surgery
Surgical procedures aimed at producing major WEIGHT REDUCTION in patients with MORBID OBESITY.
Bariatrics
Activities related to WEIGHT REDUCTION in patients with OBESITY. Treatment methods include DIET; EXERCISE; BEHAVIOR MODIFICATION; medications; and BARIATRIC SURGERY.
Serum Amyloid A Protein
An ACUTE PHASE REACTION protein present in low concentrations in normal sera, but found at higher concentrations in sera of older persons and in patients with AMYLOIDOSIS. It is the circulating precusor of amyloid A protein, which is found deposited in AA type AMYLOID FIBRILS.
Bromcresol Purple
An indicator and reagent. It has been used for several purposes including the determination of serum albumin concentrations
Serum Sickness
Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria. When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.
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