Advertisement

Topics

Rosuvastatin- and Heparin-Loaded Poly(L-Lactide-Co-Caprolactone) Nanofibre Aneurysm Stent Promotes Endothelialization via Vascular Endothelial Growth Factor Type A Modulation.

07:00 EST 7th November 2018 | BioPortfolio

Summary of "Rosuvastatin- and Heparin-Loaded Poly(L-Lactide-Co-Caprolactone) Nanofibre Aneurysm Stent Promotes Endothelialization via Vascular Endothelial Growth Factor Type A Modulation."

This study explored a new rosuvastatin calcium- and heparin-loaded poly(L-lactide-co-caprolactone) (PLCL) scaffold for covered stents in treating aneurysms. The mechanism of rosuvastatin-induced endothelialization via VEGF-A elevation was further explored.

Affiliation

Journal Details

This article was published in the following journal.

Name: ACS applied materials & interfaces
ISSN: 1944-8252
Pages:

Links

DeepDyve research library

PubMed Articles [3413 Associated PubMed Articles listed on BioPortfolio]

In Vivo Pharmacokinetics of Celecoxib Loaded Endcapped PCLA-PEG-PCLA Thermogels in Rats after Subcutaneous Administration.

Injectable thermogels based on poly(ε-caprolactone-co-lactide)-b-poly(ethylene glycol)-b-poly(ε-caprolactone-co-lactide) (PCLA-PEG-PCLA) containing an acetyl- or propyl endcap and loaded with celeco...

Synthesis and characterization of salen-Ti(IV) complex and application in the controllable polymerization of D, L-lactide.

Poly(lactic acid) has been extensively investigated in the biomedical field because of its good biocompatibility and biodegradability. As an important method of poly(lactic acid) synthesis, metal comp...

Drug-loaded poly(L-lactide)/lignin stereocomplex film for enhancing stability and sustained release of trans-resveratrol.

We report a new drug-loaded film for blending poly(L-lactide) (PLLA) with lignin-based functional filler, which enhanced stability and sustained release of trans-resveratrol (trans-RSV). In addition, ...

Papain Loaded Poly(ε-Caprolactone) Nanoparticles: In-silico and In-Vitro Studies.

Papain is a protease enzyme with therapeutic properties that are very valuable for medical applications. Poly(ε-caprolactone) (PCL) is an ideal polymeric carrier for controlled drug delivery systems...

Doxorubicin-loaded poly(ε-caprolactone)-Pluronic micelle for targeted therapy of esophageal cancer.

There is still lack of effective treatment of esophageal cancer, and it is urgently necessary to develop a new programs to treat this disease. More and more evidence suggests that the combination of 2...

Clinical Trials [1362 Associated Clinical Trials listed on BioPortfolio]

Safety Study of Polylactide-Caprolactone-Trimethylenecarbonate Copolymer for Post-Operative Adhesion Prophylaxis

The purpose of this study is to compare adhesion prophylaxis with polylactide-caprolactone-trimethylenecarbonate copolymer to icodextrin 4% in terms of safety, side effects and usability i...

Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation 2

In the stage of randomized controlled study, our purpose is to obtain the Intraoperative anticoagulation program supported by evidence-based medicine.

Long-term Evaluation of Primary Trapeziectomy and Placement of a RegJoint Implant in the Treatment of Rhizarthrosis

In a society based on the use of everyday tools and objects, the loss of function of one or both thumbs due to Rhizarthrosis can drastically reduce the quality of life. Many patients are r...

A Study of Ezetimibe Added On to Rosuvastatin Versus Up Titration of Rosuvastatin in Patients With Hypercholesterolemia

A study to evaluate the low-density lipoprotein cholesterol (LDL-C) lowering efficacy of the addition of ezetimibe to rosuvastatin compared with doubling dose of rosuvastatin in patients t...

Safety Study of FluMist With and Without Ampligen

The purpose of this study is to evaluate FluMist with and without Ampligen in healthy volunteers.

Medical and Biotech [MESH] Definitions

A poly(A) binding protein that is involved in promoting the extension of the poly A tails of MRNA. The protein requires a minimum of ten ADENOSINE nucleotides in order for binding to mRNA. Once bound it works in conjunction with CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR to stimulate the rate of poly A synthesis by POLY A POLYMERASE. Once poly-A tails reach around 250 nucleotides in length poly(A) binding protein II no longer stimulates POLYADENYLATION. Mutations within a GCG repeat region in the gene for poly(A) binding protein II have been shown to cause the disease MUSCULAR DYSTROPHY, OCULOPHARYNGEAL.

Coagulant substances inhibiting the anticoagulant action of heparin.

Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms.

A poly(ADP-ribose) polymerase that contains two ZINC FINGERS in its N-terminal DNA-binding region. It modifies NUCLEAR PROTEINS involved in chromatin architecture and BASE EXCISION REPAIR with POLY ADENOSINE DIPHOSPHATE RIBOSE.

Not an aneurysm but a well-defined collection of blood and CONNECTIVE TISSUE outside the wall of a blood vessel or the heart. It is the containment of a ruptured blood vessel or heart, such as sealing a rupture of the left ventricle. False aneurysm is formed by organized THROMBUS and HEMATOMA in surrounding tissue.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topics

Statins
Statins (or HMG-CoA reductase inhibitors) are a class of drug used to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. Increased cholesterol levels have been as...

Acute Coronary Syndromes ACS
Acute Coronary Syndromes (ACS) is an umbrella term for situations where the blood supplied to the heart muscle is suddenly blocked. Treatment for acute coronary syndrome includes medicines and a procedure known as angioplasty, during which doctors inflat...


Searches Linking to this Article