Skin Sensitization Induction Potential From Daily Exposure to Fragrances in Personal Care Products.

PubMed Articles [20668 Associated PubMed Articles listed on BioPortfolio]

IL-1α and IL-1β as alternative biomarkers for risk assessment and the prediction of skin sensitization potency.

Potential biomarkers of skin sensitization in RAW264.7 mouse macrophages were investigated as alternatives to animal experiments and risk assessment. The concentrations that resulted in a cell viabili...

Environmental novelty modulates the induction and expression of single injection-induced behavioral sensitization to morphine.

Opioid addiction is a growing public health problem, being currently considered an epidemic in the United States. Investigating the behavioral effects of opioids and the factors influencing their deve...

Neglected exposure route: cobalt on skin and its associations with urinary cobalt levels.

Cobalt (Co) exposure is associated with adverse health effects including skin sensitisation, asthma and interstitial lung fibrosis. Exposure to Co in industrial settings is often assessed using air sa...

A quantitative risk assessment for skin sensitizing plant protection products: Linking derived No-Effect levels (DNELs) with agricultural exposure models.

Chemical skin sensitizers produce allergic contact dermatitis, which is one of the most frequent occupational diseases associated with chemical exposures. Skin exposure is the major route of exposure ...

Industrial microbial enzyme safety: What does the weight-of-evidence indicate?

With the exception for the potential skin and eye irritating effects of some proteases, and the well-documented potential for respiratory sensitization in case of work place exposure, enzymes in gener...

Clinical Trials [10787 Associated Clinical Trials listed on BioPortfolio]

A Study To Evaluate The Contact Sensitization Potential Of Tazarotene Foam On Skin In Healthy Volunteers

This study will assess the potential of tazarotene foam to cause sensitization during a 48 hour challenge following 21 days of exposure on the skin of healthy volunteers.

Prevention of Dermatitis in Epoxy Exposed Workers

The risk of sensitization and contact dermatitis among workers exposed to epoxy resin systems (ERS) is high despite extensive preventive efforts, probably because skin exposure is often le...

A Repeat Insult Patch Test (RIPT) Study Evaluating the Sensitization Potential of Topical SM04755 Solution in Healthy Volunteers

This is a single center, randomized, controlled, within subject comparison, single dose study to determine the sensitization potential of SM04755 solution on normal skin under semi-occlusi...

The Effects of Smell on Mood and Physical Responses

The purpose of this study is to examine the body's response to relaxing and stimulating fragrances commonly used in aromatherapy.

Skin Safety Study to Evaluate the Sensitizing Potential in Healthy Volunteers

This is a single center, randomized, controlled, within subject comparison, multiple dose study to determine the sensitization potential of M518101 on normal skin under occlusive patch con...

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