Epithelial-Mesenchymal Transdifferentiation in Pediatric Lens Epithelial Cells.

07:00 EST 3rd December 2018 | BioPortfolio

Summary of "Epithelial-Mesenchymal Transdifferentiation in Pediatric Lens Epithelial Cells."

Posterior capsule opacification (PCO) is a complication after cataract surgery, particularly in children. Epithelial-mesenchymal transition (EMT) of lens epithelial cells, mediated by transforming growth factor beta (TGFβ), contributes to PCO. However, its pathogenesis in children is poorly understood. We correlated cell growth in culture with patient characteristics, studied gene expression of pediatric lens epithelial cells (pLEC), and examined the effects of TGFβ-2 on these cells in vitro.


Journal Details

This article was published in the following journal.

Name: Investigative ophthalmology & visual science
ISSN: 1552-5783
Pages: 5785-5794


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