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Disruption of the default mode network and its intrinsic functional connectivity underlies minor hallucinations in Parkinson's disease.

07:00 EST 10th December 2018 | BioPortfolio

Summary of "Disruption of the default mode network and its intrinsic functional connectivity underlies minor hallucinations in Parkinson's disease."

Minor hallucinations and well-structured hallucinations are considered in the severity continuum of the psychotic spectrum associated with Parkinson's disease. Although their chronological relationship is largely unknown, the spatial patterns of brain atrophy in these 2 forms of hallucinations partially overlap, suggesting they share similar pathophysiological processes. Functional connectivity studies show that disruption of functional networks involved in perception and attention could be relevant in the emergence of well-structured hallucinations. However, functional neuroimaging studies in patients with isolated minor hallucinations are lacking. The objectives of this study were to explore the structural and functional changes underlying minor hallucinations.

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Name: Movement disorders : official journal of the Movement Disorder Society
ISSN: 1531-8257
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