Advertisement

Topics

Therapeutic effect of nasal corticosteroids combined with nasal antihistamine on vasomotor rhinitis.

07:00 EST 5th December 2018 | BioPortfolio

Summary of "Therapeutic effect of nasal corticosteroids combined with nasal antihistamine on vasomotor rhinitis."

To observe the clinical efficacy of nasal corticosteroids combined with nasal antihistamine in the treatment of vasomotor rhinitis. One hundred and twenty vasomotor rhinitis patients were randomly divided into three groups including budesonide group, azelastine group, and budesonide and azelastine group with 40 cases in each. Nasal spray with nasal corticosteroids and nasal antihistamines was applied for combined treatment group, while the patients in budesonide group and azelastine group were given only nasal corticosteroids and nasal antihistamines, respectively. The course lasted 8 weeks, and the clinical efficacy was evaluated with the visual analogue scale (VAS) score and SF-12v2 score. VAS score of the peripheral nasal symptoms of the three groups was significantly decreased after treatment, and the difference was statistically significant compared with that before treatment (<0.05). The visual analogue scale of nasal symptoms in the combined treatment group was significantly lower than that in the budesonide group and the azelastine group. There was no statistically significant difference between the budesonide group and the azelastine group after the treatment on the VAS of the three nasal symptoms. However, compared with before treatment, the difference was statistically significant (<0.05). The visual analogue scale of nasal symptoms in the combined treatment group was higher than that in the budesonide group and the azelastine group, and the difference was statistically significant (<0.05). After treatment, there was no significant difference between budesonide group and azelastine group (>0.05). At the same time, the patients in the combined treatment group showed significant efficiency of 47.50% and total efficiency of 90.00%, which were statistically significant compared with budesonide group (30.00%,75.00%) and azelastine group (27.50, 70.00%), respectively (<0.05). But there was no significant difference between budesonide group and azelastine group (>0.05). Nasal corticosteroids and nasal antihistamine can effectively relieve the nasal symptoms of vasomotor rhinitis and improve the quality of life of patients. The effect of nasal corticosteroids was better than that of nasal antihistamine. The effect of nasal corticosteroids combined with nasal antihistamine was superior to that of single drug..

Affiliation

Journal Details

This article was published in the following journal.

Name: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
ISSN: 1001-1781
Pages: 1783-1787

Links

DeepDyve research library

PubMed Articles [16944 Associated PubMed Articles listed on BioPortfolio]

'Nasal mask' in comparison with 'nasal prongs' or 'rotation of nasal mask with nasal prongs' reduce the incidence of nasal injury in preterm neonates supported on nasal continuous positive airway pressure (nCPAP): A randomized controlled trial.

With increasing use of nCPAP, the safety and comfort associated with nCPAP have come into the forefront. The reported incidence of nasal injuries associated with the use of nCPAP is 20% to 60%. A rece...

Modified Z-plasty of the internal nasal valve - to treat mechanical nasal obstruction: How we do it.

The internal nasal valve (INV) is bound by the nasal septum, inferior turbinate and the upper lateral cartilage (ULC). It is the most important determinant of nasal airflow, and critical for nasal ...

Analysis of Patient-Perceived Nasal Appearance Evaluations Following Functional Septorhinoplasty With Spreader Graft Placement.

Spreader grafts have been shown to improve nasal airway obstruction in patients with nasal valve dysfunction; however, their use has been limited by concerns over their aesthetic penalty of widening t...

Does using a nasal barrier dressing prevent nasal injury in premature infants receiving nasal continuous positive airway pressure?

Surgical Technique for Nasal Cleft Repair.

Congenital nasal cleft is a very rare yet challenging deformity to reconstruct. Atypical craniofacial clefts that involve the nasal ala are designated as number 1 and number 2 under the Tessier classi...

Clinical Trials [7489 Associated Clinical Trials listed on BioPortfolio]

The Effectiveness of Nasal Corticosteroids Versus Placebo in Nasal Obstruction in Patients With Nasal Septal Deviation

The purpose of this project is to determine if intranasal corticosteroids have an effect on nasal obstruction in patients with nasal septal deviation.

Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposis

The aim of this present study is to investigate the use of benralizumab as treatment for severe nasal polyposis. The effect of benralizumab on nasal polyps will be assessed over a 56 weeks...

Investigation of the Efficacy and Safety of Concomitant Administration of Ciclesonide Nasal Spray and Azelastine Nasal Spray in Patients (18 Years or Older) With Perennial Allergic Rhinitis (PAR) Not Adequately Controlled on an Intranasal Corticosteroid o

- The primary objective of this study is to evaluate the efficacy of the concomitant administration of ciclesonide nasal spray and azelastine nasal spray versus ciclesonide nasa...

Effect of Intranasal Corticosteroids on Systemic Allergen Specific IgE

Evaluation of the effect of fluticasone propionate vs placebo applied as nasal spray on the increase of allergen-specific serum IgE levels following nasal exposure to recombinant allergens...

Assessment of Intranasal Steroids in Allergic Rhinitis When Used Alone or in Combination With an Oral Antihistamine (Study P03270)(COMPLETED)

This is a Phase 4, non-comparative, open-label, multi-center study. It is designed to determine the effectiveness of regular intranasal steroid use in alleviating allergic rhinitis nasal ...

Medical and Biotech [MESH] Definitions

Fluid obtained by irrigation or washout of the nasal cavity and NASAL MUCOSA. The resulting fluid is used in cytologic and immunologic assays of the nasal mucosa such as with the NASAL PROVOCATION TEST in the diagnosis of nasal hypersensitivity.

The proximal portion of the respiratory passages on either side of the NASAL SEPTUM. Nasal cavities, extending from the nares to the NASOPHARYNX, are lined with ciliated NASAL MUCOSA.

Application of allergens to the nasal mucosa. Interpretation includes observation of nasal symptoms, rhinoscopy, and rhinomanometry. Nasal provocation tests are used in the diagnosis of nasal hypersensitivity, including RHINITIS, ALLERGIC, SEASONAL.

Diagnostic measurement of the nose and its cavity through acoustic reflections. Used to measure nasal anatomical landmarks, nasal septal deviation, and nasal airway changes in response to allergen provocation tests (NASAL PROVOCATION TESTS).

The partition separating the two NASAL CAVITIES in the midplane. It is formed by the SEPTAL NASAL CARTILAGE, parts of skull bones (ETHMOID BONE; VOMER), and membranous parts.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topics

Allergies
The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cau...

Pharmacy
Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...


Searches Linking to this Article