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MicroRNA biomarkers for patients with muscle-invasive bladder cancer undergoing selective bladder sparing trimodality treatment.

07:00 EST 21st December 2018 | BioPortfolio

Summary of "MicroRNA biomarkers for patients with muscle-invasive bladder cancer undergoing selective bladder sparing trimodality treatment."

Trimodality therapy with maximal transurethral resection of bladder tumor and definitive chemoradiation reserving cystectomy for salvage of local recurrence is an accepted treatment alternative to upfront cystectomy for selected patients with muscle invasive bladder cancer. There is a need for molecular biomarkers to predict which patients will respond to bladder preservation therapy.

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This article was published in the following journal.

Name: International journal of radiation oncology, biology, physics
ISSN: 1879-355X
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Medical and Biotech [MESH] Definitions

Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. URINARY INCONTINENCE may or may not be present.

Tumors or cancer of the URINARY BLADDER.

A factor associated with the well-being of living organisms that is used as a measure of environmental change and or influence. For example, aldehyde dehydrogenase expression in earthworm tissue is used as an indication of heavy metal pollution in soils. Distinguish from BIOMARKERS.

A HERNIA-like condition in which the weakened pelvic muscles cause the URINARY BLADDER to drop from its normal position. Fallen urinary bladder is more common in females with the bladder dropping into the VAGINA and less common in males with the bladder dropping into the SCROTUM.

A uterine tumor derived from persistent gestational TROPHOBLASTS, most likely after a molar pregnancy (HYDATIDIFORM MOLE). Invasive hyadatiform mole develops in about 15% of patients after evacuation of a complete mole and less frequently after other types of gestation. It may perforate the MYOMETRIUM and erode uterine vessels causing hemorrhage.

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