Evaluation of activity and potential for development of antimicrobial resistance to a new tinted 2% chlorhexidine gluconate / 70% isopropyl alcohol film-forming sterile preoperative skin preparation.
Summary of "Evaluation of activity and potential for development of antimicrobial resistance to a new tinted 2% chlorhexidine gluconate / 70% isopropyl alcohol film-forming sterile preoperative skin preparation."
Chlorhexidine gluconate (CHG) is routinely used for skin antisepsis before surgery. Its activity may be affected by formulation ingredients and the presence of organic matter such as blood and proteins. This in vitro study was designed to evaluate the antimicrobial activity of a new CHG skin prep containing a film-forming copolymer, and detect its potential for development of resistance and the potential for cross-resistance to antibiotics after CHG exposure.
Affiliation
Journal Details
This article was published in the following journal.
Name: Journal of global antimicrobial resistance
ISSN: 2213-7173
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/30583012
- DOI: http://dx.doi.org/10.1016/j.jgar.2018.12.008
PubMed Articles
In Vitro Antimicrobial Effect of Bioadhesive Oral Membrane with Chlorhexidine Gel.
This study aimed to evaluate in vitro the antimicrobial effect of a bioadhesive chitosan-based oral membrane with chlorhexidine for local treatment of infections in the oral tissues. Five oral membran...
In this study, chlorhexidine-loaded poly(ε-caprolactone) nanospheres (CHX-NS) were prepared and successfully coated on the urinary catheters. Properties of CHX-NS were evaluated including drug loadin...
A series of aminothiazolyl norfloxacin analogues as a new type of potential antimicrobial agents were synthesized and screened for their antimicrobial activities. Most of the prepared compounds exhibi...
A brief appraisal of computational modeling of antimicrobial peptides' activity.
We present a brief overview of computer simulations over the span of last two decades that have made some serious attempts in providing key insights toward the mechanistic aspects of antimicrobial pep...
Changes in resistance to and antimicrobial activity of antibiotics during in vitro human digestion.
This study was conducted to determine the changes in antimicrobial activity of antibiotics (tetracycline, ofloxacin, and penicillin) and in resistance of Staphylococcus aureus RN 4220 (SA RN4220) and ...
Clinical Trials
The development of surgical site infections (SSI) in clean-contaminated surgery is regarded as being preventable. Known to be effective in the prevention of surgical site infection are the...
Inter-Mountain Project on Antimicrobial Resistance and Therapy (IMPART)
This is a four-year study, funded by the Center for Disease Control and Prevention, related to antimicrobial resistance in rural communities. The project consists of four components: A) ...
Clinical Performance of a Chlorhexidine Antimicrobial Dressing
Evaluate the clinical performance of a new IV Dressing in Comparison to a standard IV Dressing
Cinnamon and Ginger in Comparison to Chlorhexidine Gluconate 0.2% on Oral Streptococcus Mutans
Chlorhexidine is the most potent chemotherapeutic agent against mutans streptococci and dental caries, however, the incidence of side effects such as teeth discoloration, staining of resto...
The purpose of this research study is to determine if omiganan 1% gel (the investigational medication in this research study) is effective and safe when compared to chlorhexidine 2% (an FD...
Medical and Biotech [MESH] Definitions
Library Collection Development
Development of a library collection, including the determination and coordination of selection policy, assessment of needs of users and potential users, collection use studies, collection evaluation, identification of collection needs, selection of materials, planning for resource sharing, collection maintenance and weeding, and budgeting.
Drug Resistance, Bacterial
The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Drug Resistance, Microbial
The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
Insecticide Resistance
The development by insects of resistance to insecticides.
Sulfamethoxazole
A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
Quick Links
Advanced Search |
Login |
Subscribe |
RSS 
Relevant Topics
Wound management
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection.
Follow and track Wound Care News on BioPortfolio:
Wound Car...
Dermatology
Acne
Dermatology
Eczema
Psoriasis
Wound Care
Dermatology is the medical specialty concerned with the diagnosis and treatment of skin disorders (Oxford Medical Dictionary).
As well as studying how the skin works, dermatology covers...
Surgical treatments
Surgery is a technology consisting of a physical intervention on tissues.
All forms of surgery are considered invasive procedures; so-called "noninvasive surgery" usually refers to an excision that does not penetrate the structure being exci...
