Imminent risk of a global shortage of heparin caused by the African Swine Flu afflicting the Chinese pig herd.

07:00 EST 24th December 2018 | BioPortfolio

Summary of "Imminent risk of a global shortage of heparin caused by the African Swine Flu afflicting the Chinese pig herd."

Most of the unfractionated and low-molecular-weight heparins available worldwide are produced by Chinese companies from porcine mucosa. China is the world's largest producer of pork and thus has plenty of raw material to produce heparins. However, the deadly African Swine Flu (ASF) outbreaks afflicting China since August 2018 may cause extensive losses on the pig heard, bringing serious consequences to the global supply of heparins. In 2008, a sudden shortage of heparin raw material resulting from a viral disease in Chinese pigs prompted adulterations responsible for 80 deaths and hundreds of adverse events. This incident revealed the fragility of such a supply chain mostly based on a single animal raw material from a single country. A worldwide introduction of bovine mucosa heparins manufactured in different countries certainly is the feasible way to mitigate eventual shortages of these life-saving anticoagulants caused by local veterinary problems like the ASF threatening China now. This article is protected by copyright. All rights reserved.


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This article was published in the following journal.

Name: Journal of thrombosis and haemostasis : JTH
ISSN: 1538-7836


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