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Genotype-guided dosing versus conventional dosing of warfarin: A meta-analysis of 15 randomized controlled trials.

07:00 EST 28th December 2018 | BioPortfolio

Summary of "Genotype-guided dosing versus conventional dosing of warfarin: A meta-analysis of 15 randomized controlled trials."

Genotype-guided warfarin dosing algorithm is designed to predict the initial and stable dose of warfarin. However, whether this strategy is superior to conventional dosing method has not been consistently proven. To determine the benefit of genotype-guided dosing vs conventional dosing of warfarin, we performed a meta-analysis.

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This article was published in the following journal.

Name: Journal of clinical pharmacy and therapeutics
ISSN: 1365-2710
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Measurable biological parameters that serve for drug development, safety and dosing (DRUG MONITORING).

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Meta-analysis of randomized trials in which estimates of comparative treatment effects are visualized and interpreted from a network of interventions that may or may not have been evaluated directly against each other. Common considerations in network meta-analysis include conceptual and statistical heterogeneity and incoherence.

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