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Remote dosimetric auditing of clinical trials: The need for vendor specific models to convert images to dose.

07:00 EST 31st December 2018 | BioPortfolio

Summary of "Remote dosimetric auditing of clinical trials: The need for vendor specific models to convert images to dose."

A previous pilot study has demonstrated the feasibility of a novel image-based approach for remote dosimetric auditing of clinical trials. The approach uses a model to convert in-air acquired intensity modulated radiotherapy (IMRT) images to delivered dose inside a virtual phantom. The model was developed using images from an electronic portal imaging device (EPID) on a Varian linear accelerator. It was tuned using beam profiles and field size factors (FSFs) of a series of square fields measured in water tank. This work investigates the need for vendor specific conversion models for image-based auditing. The EPID measured profile and FSF data for Varian (vendor 1) and Elekta (vendor 2) systems are compared along with the performance of the existing Varian model (VM) and a new Elekta model (EM) for a series of audit IMRT fields measured on vendor 2 systems.

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This article was published in the following journal.

Name: Journal of applied clinical medical physics
ISSN: 1526-9914
Pages:

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