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Early experience with the Intrepid system for transcatheter mitral valve replacement.

08:00 EDT 1st November 2018 | BioPortfolio

Summary of "Early experience with the Intrepid system for transcatheter mitral valve replacement."

Severe mitral regurgitation is common and results in a poor prognosis in patients with either symptoms or severe ventricular dilatation. While mitral regurgitation has traditionally necessitated surgical repair or replacement, new transcatheter methods, such as the IntrepidTM transcatheter mitral valve replacement, has recently emerged. The Intrepid system is a circular, self-expanding, tri-leaflet bovine pericardial prosthesis housed within a nitinol frame. In early feasibility studies, the Intrepid prosthesis has been found to be effective for relief of mitral regurgitation and associated with functional improvement in the majority of survivors.

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Journal Details

This article was published in the following journal.

Name: Annals of cardiothoracic surgery
ISSN: 2225-319X
Pages: 792-798

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Medical and Biotech [MESH] Definitions

Surgical treatment for severe AORTIC VALVE STENOSIS. Transcatheter aortic valve replacement (TAVR) is used as an alternative option in patients who are deemed at high risk or inoperable for traditional open-heart surgery.

Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.

A type of heart valve surgery that involves the repair, replacement, or reconstruction of the annulus of the MITRAL VALVE. It includes shortening the circumference of the annulus to improve valve closing capacity and reinforcing the annulus as a step in more complex valve repairs.

Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA.

Narrowing of the passage through the MITRAL VALVE due to FIBROSIS, and CALCINOSIS in the leaflets and chordal areas. This elevates the left atrial pressure which, in turn, raises pulmonary venous and capillary pressure leading to bouts of DYSPNEA and TACHYCARDIA during physical exertion. RHEUMATIC FEVER is its primary cause.

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