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Motion induced uncertainties hamper the clinical implementation of pencil beam scanning proton therapy (PBS-PT). Prospective pre-treatment evaluations only provide multi-scenario predictions without giving a clear conclusion for the actual treatment. Therefore, in this proof-of-concept study we present a methodology for a fraction-wise retrospective 4D dose reconstruction and accumulation aiming at the evaluation of treatment quality during and after treatment.
This article was published in the following journal.
Name: Medical physics
Patient specific quality assurance is crucial to guarantee safety in proton pencil beam scanning. In current clinical practice, this requires extensive, time consuming measurements. Additionally, thes...
An accurate kernel model is of vital importance for pencil-beam dose algorithm in charged particle therapy using precise spot-scanning beam delivery, in which an accurate depiction of the low dose env...
The objective of this study is to compare forward-projected model-based iterative reconstruction solution (FIRST), a newer fully iterative CT reconstruction method, with adaptive iterative dose reduct...
For pencil beam scanned (PBS) proton therapy, analytical dose calculation engines are still typically used for the optimisation process, and often for the final evaluation of the plan. Recently howeve...
Monte Carlo (MC) dose calculation is generally superior to analytical dose calculation (ADC) used in commercial TPS to model the dose distribution especially for heterogeneous sites, such as lung and ...
This is a pilot study to assess acute toxicity in patients receiving flank irradiation using proton therapy for renal tumors.
assess the effect of using reciprocating motion with reciproc files versus adaptive motion using twisted file adaptive on postoperative pain after instrumentation of necrotic mandibular mo...
To validate a new 4D Cone Beam CT (4DCBCT) reconstruction algorithm that was developed in our research group recently in terms of its geometry and intensity accuracy through real patient s...
This phase II trial studies the side effects of intraoperative electron beam radiotherapy boost and to see how well it works in treating patients with stage I-II breast cancer undergoing s...
This is an open label phase II randomized controlled trial to determine the safety of 15 fraction vs 25 fraction pencil beam scanning proton radiotherapy after mastectomy in patients requi...
The relationship between an elicited ADAPTIVE IMMUNE RESPONSE and the dose of the vaccine administered.
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
An index for monitoring the accumulation of lipids based on the WAIST CIRCUMFERENCE measurement and the level of TRIGLYCERIDES circulating in the blood.
The science and application of a double-beam transmission interference microscope in which the illuminating light beam is split into two paths. One beam passes through the specimen while the other beam reflects off a reference mirror before joining and interfering with the other. The observed optical path difference between the two beams can be measured and used to discriminate minute differences in thickness and refraction of non-stained transparent specimens, such as living cells in culture.
Work consisting of a structured file of information or a set of logically related data stored and retrieved using computer-based means.