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Two delta class glutathione S-transferases involved in the detoxification of malathion in Bactrocera dorsalis (Hendel).

07:00 EST 4th January 2019 | BioPortfolio

Summary of "Two delta class glutathione S-transferases involved in the detoxification of malathion in Bactrocera dorsalis (Hendel)."

The oriental fruit fly, Bactrocera dorsalis (Hendel), a widespread agricultural pest, has evolved resistance to many insecticides including organophosphorus compounds. Glutathione S-transferases (GSTs) are involved in xenobiotic detoxification and insecticide resistance in many insects. However, the role of delta class GSTs in detoxifying malathion in B. dorsalis is unknown. Here, we evaluated the roles of two delta class GSTs in malathion detoxification in this species.

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This article was published in the following journal.

Name: Pest management science
ISSN: 1526-4998
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Medical and Biotech [MESH] Definitions

A subclass of transferases that transfer chemical groups containing a single carbon. These include the METHYLTRANSFERASES, the HYDROXYMETHYL AND FORMYL TRANSFERASES, the CARBOXYL AND CARBAMOYL TRANSFERASES, and the AMIDINOTRANSFERASES. EC 2.1.

Catalyzes the oxidation of GLUTATHIONE to GLUTATHIONE DISULFIDE in the presence of NADP+. Deficiency in the enzyme is associated with HEMOLYTIC ANEMIA. Formerly listed as EC 1.6.4.2.

An enzyme catalyzing the oxidation of 2 moles of glutathione in the presence of hydrogen peroxide to yield oxidized glutathione and water. EC 1.11.1.9.

A glutathione transferase that catalyzes the conjugation of electrophilic substrates to GLUTATHIONE. This enzyme has been shown to provide cellular protection against redox-mediated damage by FREE RADICALS.

A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic FREE RADICALS as well as EPOXIDES and arene oxides to GLUTATHIONE. Addition takes place at the SULFUR. It also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite.

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