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In mammals, the brain decreases in mass and volume as a function of age. The current study is, to the best of our knowledge, the first to investigate age-related changes in brain mass and volume in birds. Following perfusion, brains from young and old homing pigeons were weighed on a balance and orthogonal measurements of the telencephalon, cerebellum, and tecta were obtained with a digital caliper. It was found that older pigeons had heavier brains than younger pigeons, a difference that remained after controlling for body mass. Additionally, older pigeons had on average greater estimated telencephalon volumes than younger pigeons, again also after controlling for body mass. Cerebellum and right tectum volumes also differed between age groups after controlling for body mass, with older pigeons having a larger cerebellum and right tectum than younger pigeons. In sum, brains are on average heavier and larger in old pigeons, which display age-related cognitive decline, compared to young adult pigeons. The larger brain in older homing pigeons also lies in stark contrast with aging of the mammalian brain.
This article was published in the following journal.
Name: Neuroscience letters
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Volume of circulating blood in a region of the brain. It is a functional measure of the brain perfusion status which relates changes in this to changes in CEREBROVASULAR CIRCULATION that are often seen in brain diseases.
The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.
Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles.
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.