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Analysis and classification of kidney stones based on Raman spectroscopy.

08:00 EDT 9th August 2018 | BioPortfolio

Summary of "Analysis and classification of kidney stones based on Raman spectroscopy."

The number of patients with kidney stones worldwide is increasing, and it is particularly important to facilitate accurate diagnosis methods. Accurate analysis of the type of kidney stones plays a crucial role in the patient's follow-up treatment. This study used microscopic Raman spectroscopy to analyze and classify the different mineral components present in kidney stones. There were several Raman changes observed for the different types of kidney stones and the four types were oxalates, phosphates, purines and L-cystine kidney stones. We then combined machine learning techniques with Raman spectroscopy. KNN and SVM combinations with PCA (PCA-KNN, PCA-SVM) methods were implemented to classify the same spectral data set. The results show the diagnostic accuracies are 96.3% for the PCA-KNN and PCA-SVM methods with high sensitivity (0.963, 0.963) and specificity (0.995,0.985). The experimental Raman spectra results of kidney stones show the proposed method has high classification accuracy. This approach can provide support for physicians making treatment recommendations to patients with kidney stones.

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Journal Details

This article was published in the following journal.

Name: Biomedical optics express
ISSN: 2156-7085
Pages: 4175-4183

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Medical and Biotech [MESH] Definitions

Analysis of the intensity of Raman scattering of monochromatic light as a function of frequency of the scattered light.

Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE.

A chronic inflammatory condition of the KIDNEY resulting in diffuse renal destruction, a grossly enlarged and nonfunctioning kidney associated with NEPHROLITHIASIS and KIDNEY STONES.

Stones in the URETER that are formed in the KIDNEY. They are rarely more than 5 mm in diameter for larger renal stones cannot enter ureters. They are often lodged at the ureteral narrowing and can cause excruciating renal colic.

A non-hereditary KIDNEY disorder characterized by the abnormally dilated (ECTASIA) medullary and inner papillary portions of the collecting ducts. These collecting ducts usually contain CYSTS or DIVERTICULA filled with jelly-like material or small calculi (KIDNEY STONES) leading to infections or obstruction. It should be distinguished from congenital or hereditary POLYCYSTIC KIDNEY DISEASES.

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