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Serum metabolome is associated with nasopharyngeal microbiota and disease severity among infants with bronchiolitis.

07:00 EST 9th January 2019 | BioPortfolio

Summary of "Serum metabolome is associated with nasopharyngeal microbiota and disease severity among infants with bronchiolitis."

Emerging evidence suggests relations of nasopharyngeal metabolome and microbiota with bronchiolitis severity. However, the influence of host systemic metabolism on disease pathobiology remains unclear. We aimed to examine metabolome profiles and their association with higher severity, defined by use of positive pressure ventilation (PPV), in infants hospitalized for bronchiolitis.

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This article was published in the following journal.

Name: The Journal of infectious diseases
ISSN: 1537-6613
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Medical and Biotech [MESH] Definitions

A severity of disease classification system designed to measure the severity of disease for patients aged 15 and over admitted to intensive care units.

Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria. When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.

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A member of the family PARVOVIRIDAE, subfamily PARVOVIRINAE, originally isolated from human nasopharyngeal aspirates in patients with respiratory disease.

Changes in quantitative and qualitative composition of MICROBIOTA. The changes may lead to altered host microbial interaction or homeostatic imbalance that can contribute to a disease state often with inflammation.

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