Plum-blossom needle assisted photodynamic therapy: The therapy option for the treatment of oral potentially malignant disorder in the elderly.

07:00 EST 8th January 2019 | BioPortfolio

Summary of "Plum-blossom needle assisted photodynamic therapy: The therapy option for the treatment of oral potentially malignant disorder in the elderly."

Oral leukoplakia (OLK) is one of the most common oral potentially-malignant disorders (OPMD) with complex causes, a long disease course and a high tendency for recrudescence. Although a variety of methods exist for treating this disease, canceration rates remain high. Herein, we described a case of 72-year-old male patient with OLK of the palatine mucous membrane who had achieved complete remission after being treated with five sessions of plum-blossom needle (PBN) assisted 5-aminolevulinic acid-photodynamic therapy (ALA-PDT). The patient had since been subsequently placed under close observation (>12 mo). To date, there has been no recurrence. PBN assisted PDT might be suitable for the treatment of OPMDs in patients presenting with epithelial hyperkeratosis.


Journal Details

This article was published in the following journal.

Name: Photodiagnosis and photodynamic therapy
ISSN: 1873-1597


DeepDyve research library

PubMed Articles [15162 Associated PubMed Articles listed on BioPortfolio]

Plum-blossom needling enhanced the effect of photodynamic therapy on basal cell carcinoma.

Basal cell carcinoma (BCC) often occurs in the face of middle and old aged people. Given its particular location, aminolevulinic acid-photodynamic therapy (ALA-PDT) is often applied in cosmetology and...

Photodynamic therapy as an alternative therapeutic option for pediatric condyloma acuminata: A case series.

Improving In Vitro Photodynamic Therapy through the Development of a Novel Iron Chelating Aminolaevulinic Acid Prodrug.

Photodynamic therapy (PDT) is a light activated drug therapy that can be used to treat a number of cancers and precancers. It is particularly useful in its topical form in dermatology but improvement ...

Hypericin-assisted photodynamic therapy against anaplastic thyroid cancer.

Hypericin (HYP) extracted from St. John's wort ( Hypericum perforatum L.) is a natural photosensitizer in clinical photodynamic therapy (PDT). The PDT is one of the powerful methods for cancer treatme...

Daylight photodynamic therapy in 25 patients with actinic keratosis and evaluation of efficacy by confocal microscopy.

Daylight photodynamic therapy has been reported as having similar efficacy to conventional photodynamic therapy in actinic keratosis treatment.

Clinical Trials [14523 Associated Clinical Trials listed on BioPortfolio]

The Study of Plum-blossom Needling Enhancing Efficacy of Aminolevulinic Acid-photodynamic Therapy for Actinic Keratosis

Background Limited in the depth of absorption and penetration of photosensitizers, ALA-PDT treatment is not strong enough for thickening significantly AK lesions. Pre-study has proved that...

Photodynamic Therapy in Treating Patients With Refractory Mycosis Fungoides

This pilot phase II trial studies how well photodynamic therapy works in treating patients with mycosis fungoides that does not respond to treatment. Photodynamic therapy uses a drug, such...

Photodynamic Therapy With PD P 506 A Compared With Placebo-PDT for the Treatment of AK

The aim of this study is to investigate whether PD P 506 A-PDT is effective in treating mild to moderate AK lesions located on the head.

Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer

This pilot trial studies the side effects of endobronchial ultrasound guided interstitial photodynamic therapy work in treating patients with lung cancer that has spread to nearby tissues ...

Prophylactic Photodynamic Therapy to Organ Transplant Patients

To evaluate a possible prophylactic efficacy of photodynamic therapy on the incidence of non-melanoma skin cancer, actinic keratoses, warts and keratoses in recently organ transplanted rec...

Medical and Biotech [MESH] Definitions

The purified component of HEMATOPORPHYRIN DERIVATIVE, it consists of a mixture of oligomeric porphyrins. It is used in photodynamic therapy (HEMATOPORPHYRIN PHOTORADIATION); to treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in the use of PHOTODYNAMIC THERAPY in the United States.

Therapy assisted by the use of a horse and/or its movement, including equine-assisted psychotherapy, horseback riding, and hippotherapy.

Preliminary cancer therapy (chemotherapy, radiation therapy, hormone/endocrine therapy, immunotherapy, hyperthermia, etc.) that precedes a necessary second modality of treatment.

The use of live animal as a means of therapy

Providing an investigational therapy to a patient who is not eligible to receive that therapy in a clinical trial, but who has a serious or life-threatening illness for which other treatments are not available. Compassionate use trials allow patients to receive promising but not yet fully studied or approved therapies when no other treatment option exists. Also called expanded access trial.

Quick Search


DeepDyve research library

Searches Linking to this Article