Advertisement

Topics

New technologies provide more metabolic engineering strategies for bioethanol production in Zymomonas mobilis.

07:00 EST 19th January 2019 | BioPortfolio

Summary of "New technologies provide more metabolic engineering strategies for bioethanol production in Zymomonas mobilis."

Bioethanol has been considered as a potentially renewable energy source, and metabolic engineering plays an important role in the production of biofuels. As an efficient ethanol-producing bacterium, Zymomonas mobilis has garnered special attention due to its high sugar uptake, ethanol yield, and tolerance. Different metabolic engineering strategies have been used to establish new metabolic pathways for Z. mobilis to broaden its substrate range, remove competing pathways, and enhance its tolerance to ethanol and lignocellulosic hydrolysate inhibitors. Recent advances in omics technology, computational modeling and simulation, system biology, and synthetic biology contribute to the efficient re-design and manipulation of microbes via metabolic engineering at the whole-cell level. In this review, we summarize the progress of some new technologies used for metabolic engineering to improve bioethanol production and tolerance in Z. mobilis. Some successful examples of metabolic engineering used to develop strains for ethanol production are described in detail. Lastly, some important strategies for future metabolic engineering efforts are also highlighted.

Affiliation

Journal Details

This article was published in the following journal.

Name: Applied microbiology and biotechnology
ISSN: 1432-0614
Pages:

Links

DeepDyve research library

PubMed Articles [22180 Associated PubMed Articles listed on BioPortfolio]

Systems biology based metabolic engineering for non-natural chemicals.

Production of chemicals in microorganisms is no longer restricted to products arising from native metabolic potential. In this review, we highlight the evolution of metabolic engineering studies, from...

Water, Energy, and Carbon Footprints of Bio-ethanol from the US and Brazil.

Driven by biofuel policies, which aim to reduce greenhouse gas (GHG) emissions and increase domestic energy supply, global production and consumption of bioethanol have doubled between 2007 and 2016, ...

Lignocellulosic biomass for bioethanol: an overview on pretreatment, hydrolysis and fermentation processes.

Bioethanol is currently the only alternative to gasoline that can be used immediately without having to make any significant changes in the way fuel is distributed. In addition, the carbon dioxide (CO...

Combining protein and metabolic engineering strategies for high-level production of O-acetylhomoserine in Escherichia coli.

O-acetylhomoserine (OAH) is a promising platform chemical for the production of L-methionine and other valuable compounds. However, the relative low titer and yield of OAH greatly limit its industrial...

Engineering microbial membranes to increase stress tolerance of industrial strains.

The microbial membrane serves as a biological barrier that separates the interior of cells from the external environment, thus playing an important role in tolerance to stress conditions during indust...

Clinical Trials [7310 Associated Clinical Trials listed on BioPortfolio]

Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate Patients

The aim of this study is to perform the bone tissue engineering to reconstruct the alveolar bone defect in cleft lip and palate patients using mesenchymal stem cells from deciduous dental ...

Advanced MRI Applications for Mild Traumatic Brain Injury - UCSF

This hypothesis-generating feasibility study is being conducted to determine potential associations between a broad range of clinical neurological symptoms and MR images, data, and clinica...

Tissue Engineering for Hair Follicle Regeneration

This study is to try to maintain cultured dermal papilla cells in spherical structure in vitro before transplanting into dermis in vivo. Also, this study is aimed in clarifying actual mech...

Tissue Engineering Conjunctiva for the Treatment of Pterygium and Atretoblepharia

The purpose of this study is to determine whether tissue engineering conjunctiva is effective in the treatment of pterygium and atretoblepharia.

Dietary Strategies to Restore Gut Microbiota Diversity of Americans: Fiber vs Probiotics

The primary objective is to contrast the degree to which increased consumption of dietary fiber vs. probiotics can increase microbiota diversity and can impact microbiota production of sho...

Medical and Biotech [MESH] Definitions

Methods and techniques used to modify or select cells and develop conditions for growing cells for biosynthetic production of molecules (METABOLIC ENGINEERING), for generation of tissue structures and organs in vitro (TISSUE ENGINEERING), or for other BIOENGINEERING research objectives.

Games designed to provide information on hypotheses, policies, procedure or strategies.

A field of medicine concerned with developing and using strategies aimed at repair or replacement of damaged, diseased, or metabolically deficient organs, tissues, and cells via TISSUE ENGINEERING; CELL TRANSPLANTATION; and ARTIFICIAL ORGANS and BIOARTIFICIAL ORGANS and tissues.

Component of the NATIONAL INSTITUTES OF HEALTH. Its mission is to improve health by leading the development and accelerating the application of biomedical technologies, and integrating the physical and engineering sciences with the life sciences to advance basic research and medical care. It was established in 2000.

Methods and techniques used to genetically modify cells' biosynthetic product output and develop conditions for growing the cells as BIOREACTORS.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topic

Nutrition
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...


Searches Linking to this Article