Assessing Serum Albumin Concentration Following Exercise-Induced Fluid Shifts in the Context of the Athlete Biological Passport.

07:00 EST 28th January 2019 | BioPortfolio

Summary of "Assessing Serum Albumin Concentration Following Exercise-Induced Fluid Shifts in the Context of the Athlete Biological Passport."

The hydration status of an athlete at the time of a doping control sample collection is an important factor to consider when reviewing Athlete Biological Passports. Dehydration results in a reduction of the circulating plasma volume (PV), which may lead to artificially high values of some blood parameters. This study aimed to identify whether serum albumin could serve as a single marker of fluid shifts, which are not currently accounted for in the hematological passport. An additional marker could be used to assist experts when interpreting irregularities in the athlete biological passport (ABP).


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Name: Drug testing and analysis
ISSN: 1942-7611


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Medical and Biotech [MESH] Definitions

A condition in which albumin level in blood (SERUM ALBUMIN) is below the normal range. Hypoalbuminemia may be due to decreased hepatic albumin synthesis, increased albumin catabolism, altered albumin distribution, or albumin loss through the urine (ALBUMINURIA).

All blood proteins except albumin ( = SERUM ALBUMIN, which is not a globulin) and FIBRINOGEN (which is not in the serum). The serum globulins are subdivided into ALPHA-GLOBULINS; BETA-GLOBULINS; and GAMMA-GLOBULINS on the basis of their electrophoretic mobilities. (From Dorland, 28th ed)

A tetrameric protein, molecular weight between 50,000 and 70,000, consisting of 4 equal chains, and migrating on electrophoresis in 3 fractions more mobile than serum albumin. Its concentration ranges from 7 to 33 per cent in the serum, but levels decrease in liver disease.

Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)

Serum albumin from humans. It is an essential carrier of both endogenous substances, such as fatty acids and BILIRUBIN, and of XENOBITOICS in the blood.

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