Advertisement

Topics

Boosting the effect of reward on cognitive control using TMS over the left IFJ.

07:00 EST 2nd February 2019 | BioPortfolio

Summary of "Boosting the effect of reward on cognitive control using TMS over the left IFJ."

Although an enhancing effect of reward on cognitive performance has been observed consistently, its neural underpinnings remain elusive. Recent evidence suggests that the inferior frontal junction (IFJ) may be a key player underlying such an enhancement by integrating motivational processes and cognitive control. However, its exact role and in particular a potential causality of IFJ activation is still unclear. In the present study, we therefore investigated the causal contributions of the left IFJ in motivated task switching by temporarily disrupting its activity using continuous theta burst stimulation (cTBS, Exp.1) or 1Hz repetitive transcranial magnetic stimulation (rTMS, Exp.2). After TMS application over the left IFJ or a control site (vertex), participants performed a switch task in which numbers had to be judged by magnitude or parity. Different amounts of monetary rewards (high vs low) were used to manipulate the participants' motivational states. We measured reaction times and error rates. Irrespective of TMS stimulation, participants exhibited slower responses following task switches compared to task repeats. This effect was reduced in high reward trials. Importantly, we found that disrupting the IFJ improved participants' behavioral performance in the high reward condition. For high reward trials exclusively, error rates decreased when the IFJ was modulated with cTBS or 1Hz rTMS but not after vertex stimulation. Our results suggest that the left IFJ is causally related to the increase in cognitive performance through reward.

Affiliation

Journal Details

This article was published in the following journal.

Name: Neuropsychologia
ISSN: 1873-3514
Pages:

Links

DeepDyve research library

PubMed Articles [24120 Associated PubMed Articles listed on BioPortfolio]

Differential modulation of cognitive control networks by monetary reward and punishment.

Incentives are primary determinants of if and how well an organism will perform a given behaviour. Here, we examined how incentive valence and magnitude influence task switching, a critical cognitive ...

After-effects of self-control: The reward responsivity hypothesis.

Exercising self-control can be phenomenologically aversive. Insofar as individuals strive to maintain a positive emotional state, one consequence of exercising self-control may thus be a temporarily t...

Differentiation in prefrontal cortex recruitment during childhood: Evidence from cognitive control demands and social contexts.

Emerging cognitive control during childhood is largely supported by the development of distributed neural networks in which the prefrontal cortex (PFC) is central. The present study used fNIRS to exam...

Effects of Sleep Restriction on Food-Related Inhibitory Control and Reward in Adolescents.

This experimental study evaluated associations between sleep duration, food-related inhibitory control, and food reward in adolescents aged 12-18 with normal weight and overweight/obesity. The potenti...

Reward-associated distractors can harm cognitive performance.

When people carry out cognitive tasks, they sometimes suffer from distractions, that is, drops in performance that occur close in time to task-irrelevant stimuli. In this research, we examine how the ...

Clinical Trials [11467 Associated Clinical Trials listed on BioPortfolio]

Evaluation of Metabolism-Boosting Beverages

The purpose of this study is to assess the effect of Metabolism-boosting Beverages (MBB) containing green tea extract with a standardized amount of epigallocatechin gallate (EGCG) and caff...

Attentional Biases, Reward Sensitivity, and Cognitive Control in Adults With Bipolar Disorder

The purpose of this study is to use eye-tracking technology to study attentional biases, reward sensitivity, and cognitive control in adult patients with bipolar disorder with or without a...

Novel Cross-Species Neurophysiological Assays of Reward and Cognitive Domains

The overarching goal of this multi-disciplinary research program is to develop and optimize new cross-species translational assessments of reward and cognition that will not only be assess...

Effect of Cobicistat Versus Ritonavir Boosting on the Brain Permeation of Darunavir in HIV-infected Individuals

The purpose of this study is to assess whether a boosting by cobicistat results in similar concentrations of darunavir in the brain compared to a boosting by ritonavir.

Effect of Attention Training or SSRIs on Symptoms and Neural Activation in Social Anxiety

The purpose of this study is to determine the clinical efficacy and neuro-cognitive mechanisms of Gaze-Contingent Usic Reward Therapy for social anxiety disorder, compared with treatment w...

Medical and Biotech [MESH] Definitions

Tendency toward a lessened strength of response due to practice or activity. It is independent of the effect of reward and is a direct function of time interval since the last response and the number of preceding responses.

A set of cognitive functions that controls complex, goal-directed thought and behavior. Executive function involves multiple domains, such as CONCEPT FORMATION, goal management, cognitive flexibility, INHIBITION control, and WORKING MEMORY. Impaired executive function is seen in a range of disorders, e.g., SCHIZOPHRENIA; and ADHD.

The tendency to devalue an outcome as a function of its temporal delay or probability of achievement. It can be evaluated in a psychological paradigm that involves the choice between receiving a smaller immediate reward or a larger delayed reward, and may be used to provide a measure of impulsive behavior.

Any situation where an animal or human is trained to respond differentially to two stimuli (e.g., approach and avoidance) under reward and punishment conditions and subsequently trained under reversed reward values (i.e., the approach which was previously rewarded is punished and vice versa).

An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article