Successful management of primary immune thrombocytopenia with romiplostim during open heart surgery in a hemodialysis patient.

07:00 EST 1st January 2019 | BioPortfolio

Summary of "Successful management of primary immune thrombocytopenia with romiplostim during open heart surgery in a hemodialysis patient."

A 66-year-old male undergoing maintenance hemodialysis presented with mild thrombocytopenia. He also had aortic valve stenosis and required aortic valve replacement. In addition, he required anticoagulation therapy with warfarin because of chronic subclavian artery occlusion. He was eventually diagnosed with immune thrombocytopenic purpura (ITP), although there were no bleeding tendencies. The patient was preoperatively treated with thrombopoietin receptor agonist (romiplostim) because of the risk of bleeding complication during cardiac surgery. The platelet count rapidly increased with low-dose romiplostim, and no thrombotic complication occurred. During surgery, no significant bleeding complications were observed. This report suggests that romiplostim is a useful treatment option for the management of bleeding complication during cardiac surgery in a hemodialysis patient with ITP.


Journal Details

This article was published in the following journal.

Name: [Rinsho ketsueki] The Japanese journal of clinical hematology
ISSN: 0485-1439
Pages: 28-32


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