Omadacycline - The Newest Tetracycline.

07:00 EST 7th February 2019 | BioPortfolio

Summary of "Omadacycline - The Newest Tetracycline."

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Journal Details

This article was published in the following journal.

Name: The New England journal of medicine
ISSN: 1533-4406
Pages: 588-589


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PubMed Articles [277 Associated PubMed Articles listed on BioPortfolio]

Omadacycline Enters the Ring: A New Antimicrobial Contender.

Omadacycline is a novel aminomethylcycline seeking approval for treatment of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections. This article reviews existin...

Omadacycline: A novel tetracycline derivative with oral and intravenous formulations.

Omadacycline, an aminomethylcycline, is a novel member of the tetracycline class of antibiotics. It has received approval by the U.S. Food and Drug Administration (FDA) for treatment of community-acqu...

Omadacycline for Community-Acquired Bacterial Pneumonia.

Omadacycline, a new once-daily aminomethylcycline antibiotic agent that can be administered intravenously or orally, reaches high concentrations in pulmonary tissues and is active against common patho...

Omadacycline: First Global Approval.

Paratek Pharmaceuticals are developing omadacycline (NUZYRA™), a first-in-class orally active aminomethylcycline antibacterial, as a treatment for various bacterial infections. The drug, which is av...

Surveillance of omadacycline activity tested against clinical isolates from the United States and Europe: Results from the SENTRY Antimicrobial Surveillance Programme, 2017.

Omadacycline is an aminomethylcycline antibacterial (oral and intravenous once-daily formulation) that recently (October 2018) received FDA approval for the treatment of acute bacterial skin and skin ...

Clinical Trials [100 Associated Clinical Trials listed on BioPortfolio]

Omadacycline vs Moxifloxacin for the Treatment of CABP (EudraCT #2013-004071-13)

The purpose of this study is to evaluate the safety and efficacy of omadacycline as compared to moxifloxacin in the treatment of adults with community-acquired bacterial pneumonia.

Oral Omadacycline vs. Oral Nitrofurantoin for the Treatment of Cystitis

The purpose of this study is to evaluate the safety and efficacy of oral omadacycline as compared to oral nitrofurantoin in the treatment of female adults with cystitis.

Oral Omadacycline vs. Oral Linezolid for the Treatment of ABSSSI

The purpose of this study is to evaluate the safety and efficacy of omadacycline as compared to linezolid in the treatment of adults with acute bacterial skin and skin structure infections...

IV or IV/PO Omadacycline vs. IV/PO Levofloxacin for the Treatment of Acute Pyelonephritis

The purpose of this study is to evaluate the safety and efficacy of IV or IV/PO omadacycline as compared to IV or IV/PO levofloxacin in the treatment of female adults with acute pyelonephr...

Randomised Double Blind Crossover Placebo Controlled Study to Evaluate the Efficacy of Tetracycline in Epidermolysis Bullosa

Epidermolysis Bullosa(EB) is an inherited bullous disease. Tetracycline is believed to have anti inflammatory properties. 20 patients with EB older than 13 years will be treated for 4 mo...

Medical and Biotech [MESH] Definitions

A semisynthetic antibiotic related to TETRACYCLINE. It is more readily absorbed than TETRACYCLINE and can be used in lower doses.

A TETRACYCLINE analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant STAPHYLOCOCCUS infections.

Nonsusceptibility of bacteria to the action of TETRACYCLINE which inhibits aminoacyl-tRNA binding to the 30S ribosomal subunit during protein synthesis.

A TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time.

A pyrrolidinylmethyl TETRACYCLINE.

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