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Recently, the attention of researchers to the study of the properties of human saliva as a material with unique properties and diagnostic capabilities has increased. The purpose of the study: the study of the relationship between the biochemical composition of saliva and blood plasma is normal. 107 volunteers participated in the study, including 46 women (age 37.2 ± 3.9 years) and 61 men (age 36.1 ± 2.8 years). In all samples of saliva and blood plasma, 23 biochemical parameters were determined, including mineral and protein composition, enzyme activity, as well as indices of endogenous intoxication and lipid peroxidation. Nonparametric statistical methods are used to process the data obtained. It is shown that it is difficult to establish a unique relationship between the biochemical parameters of saliva and blood plasma. The calculation of the Spearman correlation coefficients has shown that only 7 of the 23 parameters demonstrate a weak correlation between the content in saliva and plasma. In general, the definition of saliva can have an independent diagnostic value, in this case, the parallel with the composition of serum and plasma is not appropriate. Nevertheless, the use of saliva in clinical laboratory diagnostics is associated with the need to establish criteria for the norm and pathology for each biochemical parameter.
This article was published in the following journal.
Name: Klinicheskaia laboratornaia diagnostika
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