Delayed Anaphylaxis to Mammalian Meat: A Fascinating Disease and Captivating Story.

08:00 EDT 1st October 2018 | BioPortfolio

Summary of "Delayed Anaphylaxis to Mammalian Meat: A Fascinating Disease and Captivating Story."

Delayed anaphylaxis to mammalian meat is a newly recognized IgE-mediated syndrome associated with Lone Star tick bites. IgE-mediated anaphylaxis classically occurs within one hour of exposure to the allergen, which is typically a protein epitope. However, in this disease, circulating antibodies to a carbohydrate, alpha-gal (galactose-alpha-1,3-galactose), stimulate the anaphylactic cascade with hives, diarrhea, abdominal cramps, respiratory distress and anaphylactic shock developing after ingestion of beef, pork or lamb meat. The delayed onset of symptoms three to six hours after ingestion of meat is unique. Recognition and understanding of this disease is important for treating and educating patients with suggestive symptoms. Avoidance of red meat is the recommended therapy.


Journal Details

This article was published in the following journal.

Name: South Dakota medicine : the journal of the South Dakota State Medical Association
ISSN: 0038-3317
Pages: 463-465


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