Short-term tranexamic acid treatment reduces in-hospital mortality in aneurysmal sub-arachnoid hemorrhage: A multicenter comparison study.

07:00 EST 7th February 2019 | BioPortfolio

Summary of "Short-term tranexamic acid treatment reduces in-hospital mortality in aneurysmal sub-arachnoid hemorrhage: A multicenter comparison study."

Recurrent bleeding is one of the major causes of morbidity and mortality in patients with aneurysmal subarachnoid hemorrhage (aSAH). Antifibrinolytic therapy is known to reduce recurrent bleeding, however, its beneficial effect on outcome remains unclear. The effect of treatment with tranexamic acid (TXA) until aneurysm treatment on clinical outcome is evaluated.


Journal Details

This article was published in the following journal.

Name: PloS one
ISSN: 1932-6203
Pages: e0211868


DeepDyve research library

PubMed Articles [39270 Associated PubMed Articles listed on BioPortfolio]

Risk stratification for short-term mortality at hospital admission for acute exacerbations of COPD.

Exacerbations of chronic obstructive pulmonary disease (ECOPD) are associated with increased in-hospital and short-term mortality. Developing an easy-to-use model to predict adverse outcomes will be u...

Safety of Tranexamic Acid During Pediatric Trauma: A Nationwide Database Study.

The present study aimed to examine the association between tranexamic acid use and adverse effects (seizures, thromboembolism, and renal dysfunction) in a pediatric trauma population using a national ...

Tranexamic Acid Ameliorates Non-melanoma Skin Cancer Induced by Long-term Ultraviolet A Irradiation.

To date, there have been no treatments developed to ameliorate non-melanoma skin cancer induced by long-term exposure to ultraviolet A (UVA) irradiation. In this study, we examined the effects of tran...

Effects of Tranexamic Acid on Short-term and Long-term Outcomes of On-pump Coronary Artery Bypass Grafting: Randomized Trial and 7-Year Follow-Up.

Safety evaluations of tranexamic acid (TXA) remain sparse, especially with respect to its impact on long-term outcomes in patients undergoing on-pump coronary artery bypass grafting (CABG). We hypothe...

Tranexamic acid and perioperative bleeding in children: what do we still need to know?

Perioperative bleeding and blood product transfusion are associated with significant morbidity and mortality. Prevention and optimal management of bleeding decreases risk and lowers costs. Tranexamic ...

Clinical Trials [15842 Associated Clinical Trials listed on BioPortfolio]

TRial to EvaluAte Tranexamic Acid Therapy in Thrombocytopenia

The purpose of this study is to test whether giving tranexamic acid to patients receiving treatment for blood cancers reduces the risk of bleeding or death, and the need for platelet trans...

Tranexamic Acid in Surgery of Advanced Ovarian Cancer

The purpose of the study is to determine if a standardized single dose tranexamic acid given intravenously immediately preoperatively reduces the perioperative bleeding volume and reduces ...

Tranexamic Acid in Preventing Postpartum Hemorrhage in High Risk Pregnancies During Elective Cesarean Section

postpartum hemorrhage (PPT) represents one of the major causes of maternal mortality . Tranexamic acid is used in many studies in management of PPH in combination with ecobolics. this stud...

Intravenous vs. Topical Tranexamic Acid in Revision THA (VITALITY-X)

The objective of this study is to evaluate and compare the effects of intravenous and topical administration of tranexamic acid during revision hip arthroplasty on blood loss, allogenic bl...

Tranexamic Acid in Total Knee Replacement

Multiple intravenous Tranexamic Acid doses can reduce postoperative blood loss and improve the functional outcome in total knee arthroplasty without tourniquet: a randomized controlled stu...

Medical and Biotech [MESH] Definitions

Antifibrinolytic hemostatic used in severe hemorrhage.

A phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.

Initial drug treatment designed to bring about REMISSION INDUCTION. It is typically a short-term and high-dose drug treatment that is followed by CONSOLIDATION CHEMOTHERAPY and then MAINTENANCE CHEMOTHERAPY.

Review of the medical necessity of hospital or other health facility admissions, upon or within a short time following an admission, and periodic review of services provided during the course of treatment.

A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.

Quick Search


DeepDyve research library

Searches Linking to this Article