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Unraveling Difficult Answers: From Genotype to Phenotype in Coronary Artery Disease.

07:00 EST 7th February 2019 | BioPortfolio

Summary of "Unraveling Difficult Answers: From Genotype to Phenotype in Coronary Artery Disease."

Genome-wide association studies (GWASs) have robustly found a correlation between coronary artery disease (CAD) and an intergenic region at locus 9p21.3. However, the mechanistic implication of this association is unknown. Recently in Cell, Lo Sardo et al. used hiPSC genome editing to demonstrate how this locus contributes to CAD predisposition.

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This article was published in the following journal.

Name: Cell stem cell
ISSN: 1875-9777
Pages: 203-205

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