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Cannabinoids differentially modulate the cortical information transmission through the sensorimotor or medial prefrontal basal ganglia circuits.

07:00 EST 8th February 2019 | BioPortfolio

Summary of "Cannabinoids differentially modulate the cortical information transmission through the sensorimotor or medial prefrontal basal ganglia circuits."

In the sensorimotor (SM) and medial prefrontal (mPF) basal ganglia (BG) circuits, the cortical information is transferred to the substantia nigra pars reticulata (SNr) through the hyperdirect trans-subthalamic pathway and through the direct and indirect trans-striatal pathways. The CB1 cannabinoid receptor, which is densely located in both BG circuits, may participate in the regulation of motor and motivational behaviours. Here, we investigated the modulation of cortico-nigral information transmission through the BG circuits by cannabinoids.

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Name: British journal of pharmacology
ISSN: 1476-5381
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Medical and Biotech [MESH] Definitions

Cortical malformations secondary to abnormal cortical maturation after CELL MIGRATION in NEUROGENESIS. This group includes injury to the cortex during later stages of cortical development such as POLYMICROGYRIA and focal cortical dysplasias.

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An interdisciplinary study dealing with the transmission of messages or signals, or the communication of information. Information theory does not directly deal with meaning or content, but with physical representations that have meaning or content. It overlaps considerably with communication theory and CYBERNETICS.

Interconnected system that is used in the automatic acquisition, storage, manipulation, movement, control, display, interchange, transmission, routing or reception of data or information, including computers, ancillary equipment, system software, support services, and related resources. (NAL Agricultural Thesaurus)

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