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Treatment Strategies for Clozapine-Induced Sialorrhea: A Systematic Review and Meta-analysis.

07:00 EST 13th February 2019 | BioPortfolio

Summary of "Treatment Strategies for Clozapine-Induced Sialorrhea: A Systematic Review and Meta-analysis."

Clozapine is the most effective medication for treatment-refractory schizophrenia. However, it has a high burden of adverse events, including common adverse events such as sialorrhea. Sialorrhea can lead to severe physical complications such as aspiration pneumonia, as well as psychological complications including embarrassment and low self-esteem. Compromised adherence and treatment discontinuation can occur due to intolerability. There have been no meta-analyses examining strategies to mitigate clozapine-induced sialorrhea.

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Name: CNS drugs
ISSN: 1179-1934
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