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A randomized controlled trial comparing crude versus heparin-bonded PRFE graft in below the knee bypass surgery for critical limb ischemia (REPLACE trial). Design and protocol.

07:00 EST 12th February 2019 | BioPortfolio

Summary of "A randomized controlled trial comparing crude versus heparin-bonded PRFE graft in below the knee bypass surgery for critical limb ischemia (REPLACE trial). Design and protocol."

While autogenous venous graft is preferable in below the knee bypass surgery for patients in critical limb ischemia, some 20% of patients will have no suitable vein for grafting, compelling a resort to artificial graft materials. Retrospective sub-group analyses within published studies comparing heparin-bonded PTFE with crude PFTE graft in below the knee bypass suggest that heparin-bonded graft offers superior long-term patency rates, but this has not been prospectively verified in patients with critical limb ischemia.

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This article was published in the following journal.

Name: Annals of vascular surgery
ISSN: 1615-5947
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