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Immunophenotypic Features of Myeloid Neoplasms Associated with Chromosome 7 Abnormalities.

07:00 EST 25th February 2019 | BioPortfolio

Summary of "Immunophenotypic Features of Myeloid Neoplasms Associated with Chromosome 7 Abnormalities."

Abnormalities involving chromosome 7 are one of the most frequent chromosomal aberrations in myeloid neoplasms including myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) and are associated with an adverse prognosis. Immunophenotyping by flow cytometry provides data that can assist in the diagnosis and classification of myeloid neoplasms. The immunophenotypic features of myeloid neoplasms with monosomy 7 or del(7q) have not been previously described in a comprehensive fashion.

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This article was published in the following journal.

Name: Cytometry. Part B, Clinical cytometry
ISSN: 1552-4957
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A myelodysplastic/myeloproliferative disorder characterized by myelodysplasia associated with bone marrow and peripheral blood patterns similar to CHRONIC MYELOID LEUKEMIA, but cytogenetically lacking a PHILADELPHIA CHROMOSOME or bcr/abl fusion gene (GENES, ABL).

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