Advertisement

Topics

Organo-selenium mediated regio- and stereoselective iodoselenylation of alkynes in an aqueous medium: simple access to (E)-β-iodoalkenyl selenides.

08:00 EDT 15th March 2019 | BioPortfolio

Summary of "Organo-selenium mediated regio- and stereoselective iodoselenylation of alkynes in an aqueous medium: simple access to (E)-β-iodoalkenyl selenides."

A method for the simple and efficient iodoselenylation of simple alkynes under mild conditions using commercially available molecular iodine (I2) and diorganoyldiselenides as starting materials has been developed. A broad range of alkynes can be employed to afford (E)-β-iodoalkenyl selenides in good to excellent yields and with high regio- and stereoselectivity without the need for any protecting groups.

Affiliation

Journal Details

This article was published in the following journal.

Name: Organic & biomolecular chemistry
ISSN: 1477-0539
Pages:

Links

DeepDyve research library

PubMed Articles [7260 Associated PubMed Articles listed on BioPortfolio]

Substrate Controlled Regio- and Stereoselective Synthesis of (Z) and (E) N-Styrylated Carbazoles, Aza-Carbazoles and γ-Carbolines via Hydroamination of Alkynes.

We report herein the substrate controlled regio- and stereoselective hydroamination of carbazoles, aza-carbazoles and γ-carbolines with functionalized aromatic as well as aliphatic alkynes in KOH/DMS...

Regio/Stereoselective Glycosylation of Diol and Polyol Acceptors in Efficient Synthesis of Neu5Ac-α-2,3-LacNPhth Trisaccharide.

A concise approach to Neu5Ac-α-2,3-LacNPhth trisaccharide derivative was developed. Firstly, the regio/stereoselective glycosylation between glycoside donors and glucoNPhth diol acceptors was investi...

Silver-Catalyzed Regio- and Stereoselective Formal Carbene Insertion into Unstrained C-C σ-Bonds of 1,3-Dicarbonyls.

A regio- and stereoselective silver-catalyzed formal carbene insertion into 1,3-dicarbonyls has been developed, using N-nosylhydrazones as diazo surrogates. Two new C-C bonds are constructed at the ca...

Regio- and Stereoselective Electrophilic Cyclization Approach for the Protecting-Group-Free Synthesis of Alkaloids Lennoxamine, Chilenine, Fumaridine, 8-Oxypseudoplamatine and 2-O-Methyloxyfagaronine.

A unified strategy for protecting-group-free synthesis of alkaloids lennoxamine, chilenine, fumaridine, 8-oxypseudoplamatine and 2-O-methyloxyfagaronine is reported. The core isoindolin-1-one and isoq...

Catalytic Regio- and Enantioselective Oxytrifluoromethylthiolation of Aliphatic Internal Alkenes by Neighboring Group Assistance.

Chiral selenide-catalyzed oxytrifluoromethylthiolation of aliphatic internal alkenes by a formally intermolecular strategy is disclosed, affording CFS 1,3-amino alcohol and 1,3-diol derivatives with h...

Clinical Trials [1050 Associated Clinical Trials listed on BioPortfolio]

Optimization of Selenoprotein P in Chinese Subjects

The purpose of this study is to determine the amount of selenium as selenomethionine that is required to optimize selenoprotein P in selenium-deficient Chinese subjects

Bupropion Stereoselective Disposition and CYP2D6-mediated Drug Interactions in Healthy Volunteers

Primary objectives: 1. To comprehensively characterize steady state stereoselective pharmacokinetics of bupropion and its primary and secondary metabolites in healthy volunteers ...

Selenium Supplementation of Patients With Cirrhosis

This study is being conducted to determine if patients with cirrhosis (liver disease) are selenium deficient. The effect of supplementation with two chemical forms of selenium on plasma se...

Selenium Supplementation of Patients With Cirrhosis

The purpose of this study is to determine whether patients with liver cirrhosis can improve their selenium nutritional status by taking supplemental selenium.

Research on Association Between Selenium Deficiencies and Change of Thyroid Function

As one of the essential micronutrients, selenium has important biological functions. However, an effective and convenient method for evaluation of selenium nutritional status has not yet b...

Medical and Biotech [MESH] Definitions

A selenium compound used as a source of SELENIUM, especially for patients that develop selenium deficiency following prolonged PARENTERAL NUTRITION.

Unstable isotopes of selenium that decay or disintegrate emitting radiation. Se atoms with atomic weights 70-73, 75, 79, 81, and 83-85 are radioactive selenium isotopes.

A group of proteins that covalently attach to selenium or SELENIUM-containing compounds.

Inorganic compounds formed through the oxidation of selenium.

Inorganic compounds that contain selenium as an integral part of the molecule.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article