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Bariatric surgery and psychotropic drugs : where are we now ?

08:00 EDT 20th March 2019 | BioPortfolio

Summary of "Bariatric surgery and psychotropic drugs : where are we now ?"

Bariatric surgery is considered an effective treatment against obesity. This intervention and the subsequent weight loss can affect several pharmacokinetic parameters leading to a possible need of dosing adjustment. Despite an increasing number of bariatric interventions, clinical recommendations are often based on theoretical principles and expert opinions. Because reliable clinical and biological parameters for adjusting psychotropic drug are not available, the use of therapeutic drug monitoring needs to be advised as a useful approach. However, it is not currently possible to predict the effect of bariatric surgery on psychotropic blood levels, and due to their important inter-individual variability, preoperative medication blood levels should be measured to ensure an adequate postoperative dosing adaptation.

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This article was published in the following journal.

Name: Revue medicale suisse
ISSN: 1660-9379
Pages: 631-635

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Medical and Biotech [MESH] Definitions

A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).

Surgical procedures aimed at producing major WEIGHT REDUCTION in patients with MORBID OBESITY.

Activities related to WEIGHT REDUCTION in patients with OBESITY. Treatment methods include DIET; EXERCISE; BEHAVIOR MODIFICATION; medications; and BARIATRIC SURGERY.

The discipline concerned with WEIGHT REDUCTION in patients with OBESITY.

A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE.

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